Prism adaptation treatment to address spatial neglect in an intensive rehabilitation program: A randomized pilot and feasibility trial.
Prism adaptation treatment to address spatial neglect in an intensive rehabilitation program: A randomized pilot and feasibility trial.
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棱镜适应治疗，解决强化康复计划中的空间忽视问题： 随机试点和可行性试验。
DOI：
10.1371/journal.pone.0245425
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发表时间：
2021
期刊：
影响因子：
3.7
通讯作者：
Harsa P
中科院分区：
文献类型：
--
作者：
Vilimovsky T;Chen P;Hoidekrova K;Petioky J;Harsa P
空间忽略是脑损伤后常见的认知障碍。棱镜适应治疗（PAT）是SN的有希望的干预措施之一，尽管与以前的研究结果不一致。我们进行了一项比较干预（PAT与Sham），旨在评估PAT在提供高强度综合脑损伤康复计划的住院康复环境中对SN视觉空间症状的疗效。共有34例继发于卒中或创伤性脑损伤的中重度SN患者被随机分配至PAT组和Sham组（活性对照组）。两组接受了10次治疗，超过两周，除了康复护理团队提供的康复治疗。使用生态仪器（凯瑟琳Bergego量表）和纸笔测试（贝尔测试，线平分测试和场景测试）测量结果。在基线、治疗后即刻、治疗后2周和治疗后4周对患者进行评估。23例（67.6%）患者完成了治疗和所有评估，并使用混合线性模型纳入最终分析。虽然两组的SN症状都有所减轻，但我们发现两组之间的改善程度没有差异。此外，PAT组和Sham组的平均SN回收率分别为39.1%和28.6%，但该差异未达到统计学显著性。因此，本研究表明，PAT可能有助于小SN护理的背景下，高度密集的住院康复计划。需要进一步的大规模研究来揭示PAT和Sham的潜在机制，以改进治疗或创建新的干预措施。
Spatial neglect (SN) is a common cognitive disorder after brain injury. Prism adaptation treatment (PAT) is one of the promising interventions for SN albeit inconsistent results from previous studies. We carried out a comparison intervention (PAT vs. Sham) and aimed to evaluate the efficacy of PAT on visuospatial symptoms of SN in an inpatient rehabilitation setting that offered a highly intensive comprehensive brain injury rehabilitation program. A total of 34 patients with moderate-to-severe SN secondary to stroke or traumatic brain injury were randomized to the PAT group and the Sham group (an active control group). Both groups received 10 sessions of treatment, over two weeks, in addition to the rehabilitation therapies provided by their rehabilitation care teams. Outcomes were measured using an ecological instrument (the Catherine Bergego Scale) and paper-and-pencil tests (the Bells Test, the Line Bisection Test and the Scene Copying Test). Patients were assessed at baseline, immediately after treatment, two weeks after treatment, and four weeks after treatment. 23 (67.6%) patients completed treatment and all the assessment sessions and were included in the final analyses using mixed linear modeling. While SN symptoms reduced in both groups, we found no difference between the two groups in the degree of improvement. In addition, the average SN recovery rates were 39.1% and 28.6% in the PAT and Sham groups, respectively, but this discrepancy did not reach statistical significance. Thus, the present study suggests that PAT may contribute little to SN care in the context of a highly intensive inpatient rehabilitation program. Further large-scale investigation is required to uncover the mechanisms underlying PAT and Sham in order to refine the treatment or create new interventions.
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影响因子：
2.2
作者：
Chen, Peii;Fyffe, Denise C.;Hreha, Kimberly
通讯作者：
Hreha, Kimberly
DOI：
10.1016/j.apmr.2004.10.029
发表时间：
2005-04-01
影响因子：
4.3
作者：
Gillen, R;Tennen, H;McKee, T
通讯作者：
McKee, T
影响因子：
2.5
作者：
Barrett, A. M.;Boukrina, Olga;Saleh, Soha
通讯作者：
Saleh, Soha
影响因子：
2.2
作者：
Chen P;Hreha K;Fortis P;Goedert KM;Barrett AM
通讯作者：
Barrett AM
影响因子：
2.7
作者：
Champod, Anne Sophie;Frank, Rachel C.;Eskes, Gail A.
通讯作者：
Eskes, Gail A.