Older patients with persistent postural-perceptual dizziness exhibit fewer emotional disorders and lower vertigo scores.
Older patients with persistent postural-perceptual dizziness exhibit fewer emotional disorders and lower vertigo scores.
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DOI：
10.1038/s41598-022-15987-w
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发表时间：
2022-07-13
影响因子：
4.6
通讯作者：
Li, Feng
中科院分区：
文献类型：
--
作者：
Zhang, Li;Jiang, Weiwei;Tang, Lu;Liu, Hongxing;Li, Feng
持续性体位感性头晕（PPPD）的临床特征因患者年龄和诱发因素的不同而不同。我们的目的是分析PPPD在不同患者年龄组和不同病因的临床特征的差异。纳入2018年12月至2021年7月南京脑科医院眩晕病房住院的PPPD患者122例。根据眩晕症状是否继发于器质性疾病，将PPPD患者分为原发性（p-）和继发性（s-） PPPD组；按年龄分组分为青年组、中年组、老年人组1和老年人组2。我们收集了每位患者的详细数据，包括头晕障碍量表（DHI）评分、精神状态和其他临床数据。男女比例为1:2。情绪障碍患病率以中年组最高（67.57%），老年组最低（老年1组48.08%，老年2组8.70%,P = 0.000）。P - pppd患者出现情绪障碍的比例显著高于s-PPPD患者（53.48% vs. 30.56%, P = 0.028）。中年组平均总DHI得分显著高于老年2组（52.86比35.04,P = 0.032），中年组贝克焦虑得分高于老年2组（38.89比27.65,P = 0.000）。中年组女性比例最高，情绪障碍患者比例最高，眩晕评分最高。情绪障碍患者比例和眩晕评分在老年人组中较低。
The clinical characteristics of persistent postural-perceptual dizziness (PPPD) vary according to patient age and inducing factors. We aimed to analyze the differences in the clinical characteristics of PPPD with different patient age groups and different etiologies. A total of 122 PPPD patients hospitalized in the vertigo ward of Nanjing Brain Hospital from December 2018 to July 2021 were enrolled. According to whether dizziness symptoms were secondary to organic diseases, PPPD patients were divided into the primary (p-) and secondary (s-) PPPD groups; subgroups were created according to age including youth group, middle-aged group, older adults group 1 and older adults 2. We collected detailed data from each patients, including scores on the Dizziness Handicap Inventory (DHI), mental state and other clinical data. The ratio of males to females was 1:2. The prevalence of emotional disorders in the middle-aged group was the highest (67.57%) and that in the older adults groups was lower (48.08% in older adults group 1 and 8.70% in older adults group 2, P = 0.000). The proportion of p-PPPD patients with emotional disorders was significantly higher than that of s-PPPD patients (53.48% vs. 30.56%, P = 0.028). The average total DHI score in the middle-aged group was significantly higher than that in older adults group 2 (52.86 vs. 35.04, P = 0.032), and the Beck anxiety score in the middle-aged group was higher than that in older adults group 2 (38.89 vs. 27.65, P = 0.000). The middle-aged group had the highest proportion of women, the highest proportion of patients with emotional disorders and the highest vertigo score. The proportion of patients with emotional disorders and the vertigo scores were lower in the older adults groups.
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影响因子：
3.3
作者：
Best, C.;Tschan, R.;Dieterich, M.
通讯作者：
Dieterich, M.
影响因子：
9.9
作者：
Powell, Georgina;Derry-Sumner, Hannah;Sumner, Petroc
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Sumner, Petroc
DOI：
10.13201/j.issn.2096-7993.2021.05.013
发表时间：
2021-05-01
影响因子：
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作者：
Yang, Li;Ding, Wei;Wu, Mei
通讯作者：
Wu, Mei
影响因子：
4.7
作者：
Fink, P;Hansen, MS;Oxhoj, ML
通讯作者：
Oxhoj, ML
影响因子：
11
作者：
Lahmann, Claas;Henningsen, Peter;Schmid, Gabriele
通讯作者：
Schmid, Gabriele