Complexity of retinal cone bipolar cells.
Complexity of retinal cone bipolar cells.
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DOI：
10.1016/j.preteyeres.2010.03.005
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发表时间：
2010-07
影响因子：
17.8
通讯作者：
Damiani, Devid
中科院分区：
文献类型：
--
作者：
Strettoi, Enrica;Novelli, Elena;Mazzoni, Francesca;Barone, Ilaria;Damiani, Devid
视网膜组织和功能的一个悬而未决的问题是对双极细胞具体执行的不同任务的理解。双极细胞是指从外部视网膜的光感受器收集信息并将信号传送到内丛状层的神经元。特别有趣的是了解视锥双极细胞对视觉信号的独特贡献，视锥双极细胞是哺乳动物视网膜的典型神经元，特别致力于接受视锥细胞的突触输入。到目前为止，在所有研究的物种中，已经表明锥体双极细胞以大约10种不同的类型出现，它们形成了不同的簇，用一组经典和现代的遗传方法进行了鉴定。这里回顾了目前的文献，说明了赋予每一种双极细胞类型独有指纹的形态、分子和结构特征的出现，最终预测了类似独特的功能特性的出现，尽管仍有部分解开。因此，视锥双极细胞之间的差异为平行通道在视网膜外部的起源奠定了基础，这些通道向内部视网膜传递关于视觉信号的对比度、颜色特征和时间特性等独立信息。
An open issue of retinal organization and function is the comprehension of the different tasks specifically performed by bipolar cells, the neurons that collect information from photoreceptors in the outer retina and convey the signal to the inner plexiform layer. Particularly interesting is to understand the unique contribution to the visual signal brought by cone bipolar cells, neurons typical of the mammalian retina and especially dedicated to receive synaptic input from cones. In all the species studied so far, it has been shown that cone bipolar cells occur in about ten different types, which form distinct clusters identified with a panel of both classical and modern genetic methods. Reviewed here is current literature illustrating the occurrence of morphological, molecular and architectural features that confer to each bipolar cell type exclusive fingerprints, ultimately predicting the emergence of similarly unique, albeit still partially unraveled, functional properties. Thus, differences among cone bipolar cells lay the ground for the genesis in the outer retina of parallel channels, which convey to the inner retina separate information, among others, about contrast, chromatic features and temporal properties of the visual signal.
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影响因子：
16.2
作者：
DeVries, Steven H.;Li, Wei;Saszik, Shannon
通讯作者：
Saszik, Shannon
影响因子：
2.5
作者：
Ghosh, KK;Bujan, S;Wässle, H
通讯作者：
Wässle, H
影响因子：
5.3
作者：
Dhingra, A;Jiang, MS;Vardi, N
通讯作者：
Vardi, N
DOI：
10.1073/pnas.96.24.14130
发表时间：
1999-11-23
影响因子：
11.1
作者：
Hack, I;Peichl, L;Brandstätter, JH
通讯作者：
Brandstätter, JH
影响因子：
2.5
作者：
Gargini, Claudia;Terzibasi, Eva;Strettoi, Enrica
通讯作者：
Strettoi, Enrica