Recruitment and Retention of Urban Pregnant Women to a Clinical Study Administering an Oral Isotope Dietary Tracer.
Recruitment and Retention of Urban Pregnant Women to a Clinical Study Administering an Oral Isotope Dietary Tracer.
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DOI：
10.1089/whr.2022.0015
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Ferrans CE
中科院分区：
文献类型：
--
作者：
Koenig MD;Tussing-Humphreys L;DeMartelly V;LaBomascus B;OjiNjideka Hemphill N;Welke L;Pezley L;Ruchob R;Hirsch B;Furlette-Koski M;Kessee N;Ferrans CE
孕妇是难以从事临床研究的弱势群体。我们报告了在城市种族/民族多样化孕妇的纵向试点研究中成功使用的招募和保留策略，其中包括口服同位素示踪剂、多次静脉穿刺、分娩后胎盘活检以及脐带血或胎盘血采集。我们采用直接策略招募年龄在 17-45 岁、处于妊娠晚期的说英语的肥胖和非肥胖孕妇。该研究需要在 32-34 和 34-36 孕周以及分娩时收集数据。策略包括与参与者和工作人员经常进行个人接触，以建立关系和信任、切实的赞赏以及研究团队在交付时在场。此外，利用医院信息技术 (IT) 服务对于确保临产和分娩 (LD) 保留率至关重要。纳入了种族（52% 黑人、23% 白人和 10% 其他）和民族（15% 西班牙裔或拉丁裔）多样化的孕妇样本。在 52 名登记的女性中，85% 的女性完成了所有手术。这是第一份关于在需要口服同位素示踪剂的纵向研究中招募和保留种族/民族多样化孕妇的成功策略的报告。最成功的策略是从招聘开始一直持续到整个妊娠晚期，通过多个接触点进行个人参与。与 LD 提供者和工作人员建立和维持关系，并利用医院 IT（包括有针对性的电子病历警报）确保了研究期间的成功保留。不适用。
Pregnant women are a vulnerable population that are difficult to engage in clinical research. We report successful recruitment and retention strategies used in a longitudinal pilot study of urban racially/ethnically diverse pregnant women that involved administration of an orally ingested isotope tracer, multiple venipunctures, biopsy of placenta after delivery, and cord or placental blood collection. We used direct strategies to recruit English-speaking obese and nonobese pregnant women aged 17–45 years, who were in the third trimester of pregnancy. The study required data collection at 32–34 and 34–36 gestational weeks and delivery. Strategies included frequent personal engagement with participants and staff to build relationships and trust, tangible appreciation, and the study team being present at delivery. In addition, leveraging hospital information technology (IT) services was critical to ensure retention through labor and delivery (LD). A racially (52% Black, 23% White, and 10% other) and ethnically (15% Hispanic or Latinx) diverse sample of pregnant women was enrolled. Of the 52 women enrolled, 85% of women completed all procedures. This is the first report of successful strategies for recruitment and retention of racially/ethnically diverse pregnant women in a longitudinal study requiring oral administration of an isotope tracer. Personal engagement with multiple touch points, starting with recruitment and continuing regularly throughout the third trimester, was the most successful strategy. Creating and maintaining relationships with the LD providers and staff and utilizing hospital IT, including targeted electronic medical record alerts, ensured successful retention for the duration of the study. Not applicable.
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影响因子：
2.3
作者：
Webster, Glenys M.;Teschke, Kay;Janssen, Patricia A.
通讯作者：
Janssen, Patricia A.
影响因子：
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影响因子：
2.2
作者：
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影响因子：
7.2
作者：
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通讯作者：
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影响因子：
3.2
作者：
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通讯作者：
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