Nonsteroidal anti-inflammatory drugs for the prevention of colon cancer.
Nonsteroidal anti-inflammatory drugs for the prevention of colon cancer.
复制标题
用于预防结肠癌的非甾体类抗炎药。
DOI:
--
复制
发表时间:
1993
期刊:
影响因子:
--
通讯作者:
H. Berkel
中科院分区:
文献类型:
--
作者:
Donna Thrner;H. Berkel
OBJECTIVE
To summarize the results of animal and human studies of the effect of nonsteroidal anti-inflammatory drugs (NSAIDs) on neoplastic growth in the colon and to outline the possible mechanisms involved.
DATA SOURCES
Research articles published in English before June 1992 were identified from MEDLINE.
STUDY SELECTION
Nine articles on the polyp-cancer sequence were reviewed, 8 on the apparent pathophysiologic aspects of tumour inhibition by NSAIDs and 22 on animal and human research into the effect of NSAIDs on colon carcinogenesis.
RESULTS
The results of animal and human research into the anticarcinogenic effect of NSAIDs suggest that the drugs are effective in preventing tumour growth in the colon.
CONCLUSIONS
Intervention studies in humans are necessary to elucidate the therapeutic possibilities of NSAIDs, particularly in populations at increased risk for the development of colon cancer.
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影响因子:
11.2
作者:
Chinthalapally;V. Rao;K. Tokumo;J. Rigotty;E. Zang;G. Kelloff;Bandaru S. Reddy
通讯作者:
Chinthalapally;V. Rao;K. Tokumo;J. Rigotty;E. Zang;G. Kelloff;Bandaru S. Reddy
影响因子:
11.2
作者:
Reddy,BS;Maruyama,H;Kelloff,G
通讯作者:
Kelloff,G
DOI:
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发表时间:
1992
期刊:
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子:
--
作者:
Singh,J;Kelloff,G;Reddy,BS
通讯作者:
Reddy,BS
影响因子:
105.7
作者:
PAGANINIHILL, A;CHAO, A;HENDERSON, BE
通讯作者:
HENDERSON, BE
DOI:
10.1093/jnci/83.5.355
发表时间:
1991-03-06
期刊:
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子:
--
作者:
ROSENBERG, L;PALMER, JR;SHAPIRO, S
通讯作者:
SHAPIRO, S