Fabrication of elastomer Pillar Arrays with Modulated Stiffness for Cellular Force Measurements.

Fabrication of elastomer Pillar Arrays with Modulated Stiffness for Cellular Force Measurements.
复制标题

DOI:
10.1116/1.3013424
复制
发表时间:
2008-11-01
期刊:
Journal of vacuum science & technology. B, Microelectronics and nanometer structures : processing, measurement, and phenomena : an official journal of the American Vacuum Society
影响因子:
--
通讯作者:
Hone J
Hone J
中科院分区:
其他
文献类型:
--
作者:
Ghassemi S;Biais N;Maniura K;Wind SJ;Sheetz MP;Hone J

文献摘要

参考文献

被引文献

相似文献

细胞环境的机械特性可以改变行为,如迁移和扩散,并控制干细胞的分化途径。在这里,我们描述了一种技术,用于制造基板,其刚度可以局部控制,而不改变细胞扩散的接触面积。基底由弹性体柱阵列组成,其中顶表面是均匀的,但柱高度在陡峭的台阶上变化。初步结果表明,在步骤边界的细胞迁移和形态的影响。
The mechanical properties of a cell's environment can alter behavior such as migration and spreading, and control the differentiation path of stem cells. Here we describe a technique for fabricating substrates whose rigidity can be controlled locally without altering the contact area for cell spreading. The substrates consist of elastomeric pillar arrays in which the top surface is uniform but the pillar height is changed across a sharp step. Preliminary results demonstrate the effects on cell migration and morphology at the step boundary.
DOI: 10.1073/pnas.0408482102
发表时间: 2005-02-15
影响因子: 11.1
作者:
du Roure, O;Saez, A;Ladoux, B
通讯作者: Ladoux, B
DOI: 10.1096/fj.07-090571
发表时间: 2008-06-01
期刊: FASEB JOURNAL
影响因子: 4.8
作者:
Xia, Nan;Thodeti, Charles K.;Ingber, Donald E.
通讯作者: Ingber, Donald E.
DOI: 10.1016/s0006-3495(00)76279-5
发表时间: 2000-07-01
影响因子: 3.4
作者:
Lo, CM;Wang, HB;Wang, YL
通讯作者: Wang, YL
DOI: 10.1529/biophysj.106.093302
发表时间: 2007-07-01
影响因子: 3.4
作者:
Tymchenko, N.;Wallentin, J.;Gold, J.
通讯作者: Gold, J.
DOI: 10.1073/pnas.0702259104
发表时间: 2007-05-15
影响因子: 11.1
作者:
Saez, Alexandre;Ghibaudo, Marion;Ladoux, Benoit
通讯作者: Ladoux, Benoit