Ictal central apneas in temporal lobe epilepsies.
Ictal central apneas in temporal lobe epilepsies.
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DOI：
10.1016/j.yebeh.2020.107434
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发表时间：
2020-11
期刊：
影响因子：
--
通讯作者：
Schuele S
中科院分区：
文献类型：
--
作者：
Tio E;Culler GW;Bachman EM;Schuele S
在接受表面视频脑电图（EEG）和心肺参数多模式记录的内侧或新皮质颞叶癫痫（TLE）患者中，检查发作性中枢性呼吸暂停（伊卡）的频率和特征。我们回顾性筛选了453例在单中心接受EEG检查的患者，包括鼻气流测量、胸腹部偏移的呼吸感应体积描记术、外周毛细血管血氧饱和度和心电图。纳入经MRI病变限于颞叶新皮质或近中结构且神经生理学数据一致的确诊TLE亚型患者或接受侵入性探查的患者。伊卡频率和特点进行了分析，在41例患者的164次癫痫发作，多模式呼吸监测。该队列中所有癫痫发作中伊卡的总发生率为79.9%。颞叶内侧和新皮质癫痫发作的发生率无显著差异（分别为79.8%和80.0%）。伊卡在33.3%的癫痫发作中先于EEG发作13 ± 11秒，在48.7%的癫痫发作中是第一个临床体征18 ± 14秒。伊卡持续时间越长，低氧血症的程度越严重。在通过MRI病变和/或颅内记录定义的TLE选择性队列中，伊卡的发生率高于文献中先前报告的发生率。多模式呼吸监测具有定位价值，并且通常耐受性良好。伊卡先于头皮记录EEG以及大量患者的临床癫痫发作。在侵入性监测期间，呼吸监测和伊卡检测更为重要，以确认记录的癫痫发作在第一个临床体征之前出现。
To examine the frequency and characteristics of ictal central apnea (ICA) in a selective cohort of patients with mesial or neocortical temporal lobe epilepsy (TLE) undergoing surface video electroencephalography (EEG) and multimodal recording of cardiorespiratory parameters. We retrospectively screened 453 patients who underwent EEG in a single center including nasal airflow measurements, respiratory inductance plethysmography of thoraco–abdominal excursions, peripheral capillary oxygen saturation, and electrocardiography. Patients with confirmed TLE subtype, either by MRI lesions limited to the temporal neocortex or mesial structures and concordant neurophysiologic data or patients who underwent invasive explorations were included. ICA frequency and characteristics were analyzed in 41 patients with 164 seizures that had multimodal respiratory monitoring. The total occurrence of ICA in all seizures in this cohort was 79.9%. No significant difference was seen between mesial and neocortical temporal lobe seizures (79.8% and 80.0%, respectively). ICA preceded EEG onset by 13 ± 11 seconds in 33.3% of seizures and was the first clinical sign by 18 ± 14 seconds in 48.7%. Longer ICA duration trended towards a more severe degree of hypoxemia. In a selective cohort of TLE defined by MRI-lesion and/or intracranial recordings, the frequency of ICA was higher than previously reported in the literature. Multimodal respiratory monitoring has localizing value and is generally well tolerated. ICA preceded both EEG on scalp recordings as well as clinical seizure onset in a substantial number of patients. Respiratory monitoring and ICA detection is even more paramount during invasive monitoring to confirm that the recorded seizure onset is seen before the first clinical sign.
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DOI：
10.1016/j.yebeh.2018.06.006
发表时间：
2018-08
期刊：
Epilepsy & behavior : E&B
影响因子：
--
作者：
Gehlbach BK;Sainju RK;Tadlock DK;Dragon DN;Granner MA;Richerson GB
通讯作者：
Richerson GB
影响因子：
9.9
作者：
Lacuey, Nuria;Hampson, Johnson P.;Lhatoo, Samden
通讯作者：
Lhatoo, Samden
影响因子：
3.4
作者：
Vilella, Laura;Lacuey, Nuria;Lhatoo, Samden D.
通讯作者：
Lhatoo, Samden D.
影响因子：
2.6
作者：
Schuele, Stephan U.;Afshari, Mitra;Gerard, Elizabeth E.
通讯作者：
Gerard, Elizabeth E.
影响因子：
3
作者：
Garcia, M;D'Giano, C;Rabinowicz, A
通讯作者：
Rabinowicz, A