A novel screening method for influenza patients using a newly developed non-contact screening system.

A novel screening method for influenza patients using a newly developed non-contact screening system.
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DOI:
10.1016/j.jinf.2010.01.005
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发表时间:
2010-04
期刊:
The Journal of infection
影响因子:
--
通讯作者:
Abe S
Abe S
中科院分区:
其他
文献类型:
--
作者:
Matsui T;Hakozaki Y;Suzuki S;Usui T;Kato T;Hasegawa K;Sugiyama Y;Sugamata M;Abe S

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在人群聚集的地方,在一种新型流感的流行季节,在确诊之前进行快速感染筛查是至关重要的。为了评估新开发的非接触性感染筛查系统在临床应用的可能性,我们对流感患者进行了筛查。该系统由筛查程序操作,通过使用非接触式派生变量的线性判别分析来操作,所述派生变量即来自激光多普勒血流计的掌脉、由10 GHz微波雷达确定的呼吸频率、以及通过热像仪测量的平均面部温度。该系统在日本自卫队中心医院的57名季节性流感(2008年至2009年)患者(≤体温35.7℃,≤38.3℃,19-40岁)和35名正常对照对象(≤体温35.5℃,≤36.9℃,21-35岁)上进行了测试。确定了一个显著的线性判别函数(P<0.001)来区分流感组和对照组(马哈拉诺比斯D-平方差=6.5%,分类错误率t&gt;=10%.该系统的阳性预测值(PPV值)为93%,高于最近仅在医院进行的热成像研究总结中报告的PPV值(PPV值和≤为65.4%)。建议的系统似乎很有希望应用于大规模聚集场所对流感患者的准确筛查。
In places of mass gathering, rapid infection screening prior to definite diagnosis is vital during the epidemic season of a novel influenza. In order to assess the possibility of clinical application of a newly developed non-contact infection screening system, we conducted screening for influenza patients. The system is operated by a screening program via a linear discriminant analysis using non-contact derived variables, i.e., palmar pulse derived from a laser Doppler blood-flow meter, respiration rate determined by a 10-GHz microwave radar, and average facial temperature measured by thermography. The system was tested on 57 seasonal influenza (2008–2009) patients (35.7 °C ≤ body temperature ≤ 38.3 °C, 19–40 years) and 35 normal control subjects (35.5 °C ≤ body temperature ≤ 36.9 °C, 21–35 years) at the Japan Self-defense Forces Central Hospital. A significant linear discriminant function (p < 0.001) was determined to distinguish the influenza group from the control group (Mahalanobis D-square = 6.5, classification error rate > 10%). The system had a positive predictive value (PPV) of 93%, which is higher than the PPV value (PPV ≤ 65.4%) reported in the recent summary of studies using only thermography performed mainly in hospitals. The proposed system appears promising for application in accurate screening for influenza patients at places of mass gathering.
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