Case Report: Bronchial artery embolization and chemoradiotherapy for central squamous cell lung carcinoma with rapid regression.
Case Report: Bronchial artery embolization and chemoradiotherapy for central squamous cell lung carcinoma with rapid regression.
复制标题
DOI：
10.3389/fonc.2022.1026087
复制
发表时间：
2022
影响因子：
4.7
通讯作者：
中科院分区：
文献类型：
--
作者：
咯血是肺癌并发症之一，介入栓塞是常见的治疗方法。然而，在抗肿瘤治疗中使用这种方法并没有官方的指导方针。在此，我们描述一个病例的病人谁是病理诊断为中央鳞状细胞肺癌。患者先后接受化疗、介入栓塞、放疗。肿瘤在介入栓塞治疗后48小时内迅速消退。此外，在放疗的7天内，肿瘤的大小缩小了50%以上。不幸的是，患者已经发展为淋巴结转移，仍在治疗中。因此，寻找合适的血管栓塞可能是减少局部肿瘤负荷的合适选择，可以考虑与其他治疗联合进行抗肿瘤治疗。患者介入治疗后的理论缺氧状态在放疗后仍产生良好的肿瘤消退。然而，迄今为止，没有相关研究报道干预和放疗后人体肿瘤免疫微环境的变化。
Interventional embolization is a common treatment for hemoptysis, one of the complications of lung cancer. However, there are no official guidelines for the use of this method in antitumor therapy. Herein, we describe a case of a patient who was pathologically diagnosed as central squamous cell lung cancer. The patient received chemotherapy, interventional embolization and radiotherapy successively. The tumor regressed rapidly within 48 hours of receipt of interventional embolization. Furthermore, the tumor decreased by more than 50% in size within 7 days during radiotherapy. Unfortunately, the patient has since developed lymph node metastases and remains under treatment. Thus, finding the suitable blood vessel embolized may be a suitable option to reduce the local tumor load and can be considered as antitumor therapy in combination with other treatments. The patient’s theoretical hypoxia state after interventional therapy still produced a good tumor regression after radiotherapy. However, so far, no related studies have reported the changes of tumor immune microenvironment in human body after intervention and radiotherapy.
登录
查看更多内容
影响因子：
45.3
作者：
Bezjak, Andrea;Temin, Sarah;Azzoli, Christopher G.
通讯作者：
Azzoli, Christopher G.
影响因子：
2.9
作者：
Seki, Akihiko;Hori, Shinichi;Maeda, Masahiko
通讯作者：
Maeda, Masahiko
影响因子：
2.9
作者：
Park, Hong Suk;Kim, Young Il;Lee, Jin Soo
通讯作者：
Lee, Jin Soo
影响因子：
2.9
作者：
HAYAKAWA, K;TANAKA, F;MISAKI, T
通讯作者：
MISAKI, T
影响因子：
9.6
作者：
Detterbeck, Frank C.;Boffa, Daniel J.;Tanoue, Lynn T.
通讯作者：
Tanoue, Lynn T.