The longitudinal association of vitamin D serum concentrations & adiposity phenotype.

The longitudinal association of vitamin D serum concentrations & adiposity phenotype.
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DOI:
10.1016/j.jsbmb.2013.12.004
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发表时间:
2014-10
影响因子:
4.1
通讯作者:
Tucker, Katherine L.
Tucker, Katherine L.
中科院分区:
生物学2区
文献类型:
--
作者:
Jamal-Allial, Aziza;Griffith, John L.;Tucker, Katherine L.

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Several cross-sectional studies have reported on the association between serum 25-hydroxy vitamin D concentrations (25(OH)D) and body mass index (BMI). We examined the longitudinal effect of BMI on serum 25(OH)D concentrations among 866 Puerto Rican adults living in the Greater Boston area: 246 men and 620 women, aged 45–75 years at baseline and 2 year. Our analyses showed negative correlations at two time points between BMI and serum 25(OH)D concentrations. The multivariate analysis showed that when predicting the change of serum 25(OH)D concentrations, baseline-BMI had significant inverse association (P<0.04) controlling for age, sex, and baseline-25 (OH)D). This association remained significant after adjusting for vitamin D supplement use, smoking, miles walking/day and alcohol intake (P<0.01). In conclusion, the major findings of the present study are obesity 1) was inversely associated with 25(OH)D at baseline; 2) with the change in serum 25(OH)D at 2-year in this population of older Puerto Rican adults living in the Boston area.
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