Brain structure in young and old East Asians and Westerners: comparisons of structural volume and cortical thickness.

Brain structure in young and old East Asians and Westerners: comparisons of structural volume and cortical thickness.
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DOI:
10.1162/jocn.2010.21513
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发表时间:
2011-05
影响因子:
3.2
通讯作者:
Sutton BP
Sutton BP
中科院分区:
医学3区
文献类型:
--
作者:
Chee MW;Zheng H;Goh JO;Park D;Sutton BP

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有一个新兴的文献表明,东亚人和西方人的认知过程不同,因为文化偏见处理信息的整体(东亚人)或分析(西方人)。为了评估这种差异伴随着大脑结构差异的可能性,我们对来自两个文化/种族群体-新加坡华人和非亚裔美国人-共140人的认知匹配的年轻人和老年人进行了一项大型比较研究。年轻的主要是白色美国成年人被发现有较高的皮质厚度在额叶,顶叶,和中颞多模态联合区在两个半球。这些发现被复制使用基于体素的形态测量应用于相同的数据集。在年轻志愿者之间观察到的皮质厚度差异在老年受试者中总体上并不显著。然而,当高性能的老年人进行比较时,组间差异是明显的。虽然观察到的灰质差异可能源于种族/文化差异引起的认知策略差异,但也考虑了涉及遗传遗产和环境因素的其他解释。
There is an emergent literature suggesting that East Asians and Westerners differ in cognitive processes because of cultural biases to process information holistically (East Asians) or analytically (Westerners). To evaluate the possibility that such differences are accompanied by differences in brain structure, we conducted a large comparative study on cognitively matched young and old adults from two cultural/ethnic groups—Chinese Singaporeans and non-Asian Americans—that involved a total of 140 persons. Young predominantly White American adults were found to have higher cortical thickness in frontal, parietal, and medial-temporal polymodal association areas in both hemispheres. These findings were replicated using voxel-based morphometry applied to the same data set. Differences in cortical thickness observed between young volunteers were not significant in older subjects as a whole. However, group differences were evident when high-performing old were compared. Although the observed differences in gray matter may be rooted in strategic differences in cognition arising from ethnic/cultural differences, alternative explanations involving genetic heritage and environmental factors are also considered.
使用基于体素的形态计量学探索跨语言词汇对大脑结构的影响。
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