Importance of Reference Muscle Selection in Quantitative Signal Intensity Analysis of T2-Weighted Images of Myocardial Edema Using a T2 Ratio Method.
Importance of Reference Muscle Selection in Quantitative Signal Intensity Analysis of T2-Weighted Images of Myocardial Edema Using a T2 Ratio Method.
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DOI：
10.1155/2015/232649
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发表时间：
2015
影响因子：
--
通讯作者：
Friedrich MG
中科院分区：
文献类型：
--
作者：
Carbone I;Childs H;Aljizeeri A;Merchant N;Friedrich MG
目标。我们研究的目的是确定各种骨骼肌作为参考区域的适用性，以计算T2 SI比，从而用T2加权图像半自动量化心肌水肿程度。方法。34例急性心肌梗死（MI）患者入组。以胸大、胸小肌、前锯肌、小冈下圆肌、肩胛下肌4块不同肌肉为参照，采用T2 - SI比值图测定心肌水肿程度。以视觉量化的心肌水肿大小作为判断真伪的标准。对照组由15名慢性心肌梗死患者组成。评估了观察者内部和观察者之间的变异性。结果。由于图像质量差，4例患者被排除在分析之外。在急性心肌梗死患者中，前锯肌与视觉分析的相关性最强（r = 0.799; P < 0.001），观察者间和观察者内变异性较低，而其他肌肉的观察者间变异性显著。相反，使用其他肌肉作为参考会导致高估水肿大小。结论。在急性心肌梗死患者中，前锯肌是测量心肌水肿程度最可靠和可重复的肌肉。
Objectives. The purpose of our study was to identify the suitability of various skeletal muscles as reference regions for calculating the T2 SI ratio for a semiautomated quantification of the extent of myocardial edema with T2-weighted images. Methods. Thirty-four patients with acute myocardial infarction (MI) were enrolled. The extent of myocardial edema was determined by T2 SI ratio map, using 4 different muscles as reference: major and minor pectoralis, serratus anterior, teres minor-infraspinatus, and subscapularis. The size of myocardial edema as visually quantified was used as the standard of truth. The control group consisted of 15 patients with chronic MI. Intra- and interobserver variability were assessed. Results. Due to poor image quality four patients were excluded from the analysis. In acute MI patients, serratus anterior muscle showed the strongest correlation with the visual analysis (r = 0.799; P < 0.001) and low inter- and intraobserver variability, while the other muscles resulted in a significant interobserver variability. In contrast, the use of other muscles as a reference led to overestimating edema size. Conclusions. In acute MI patients, serratus anterior resulted to be the most reliable and reproducible muscle for measuring the extent of myocardial edema.
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影响因子：
24
作者：
Abdel-Aty, H;Boyé, P;Schulz-Menger, J
通讯作者：
Schulz-Menger, J
影响因子：
24
作者：
Abdel-Aty, Hassan;Cocker, Myra;Friedrich, Matthias G.
通讯作者：
Friedrich, Matthias G.
影响因子：
24
作者：
Friedrich, Matthias G.;Sechtem, Udo;Schulz-Menger, Jeanette;Holmvang, Godtfred;Alakija, Pauline;Cooper, Leslie T.;White, James A.;Abdel-Aty, Hassan;Gutberlet, Matthias;Prasad, Sanjay;Aletras, Anthony;Laissy, Jean-Pierre;Paterson, Ian;Filipchuk, Neil G.;Kumar, Andreas;Pauschinger, Matthias;Liu, Peter
通讯作者：
Liu, Peter
影响因子：
37.8
作者：
Friedrich, MG;Strohm, O;Dietz, R
通讯作者：
Dietz, R
影响因子：
120.7
作者：
Eitel, Ingo;von Knobelsdorff-Brenkenhoff, Florian;Friedrich, Matthias G.
通讯作者：
Friedrich, Matthias G.