Cholesterol control in stroke prevention in Italy: a cross-sectional study in family practice
Cholesterol control in stroke prevention in Italy: a cross-sectional study in family practice
复制标题
意大利中风预防中的胆固醇控制：家庭实践横断面研究
DOI：
10.1097/01.hjr.0000161444.96302.cc
复制
发表时间：
2005
影响因子：
8.3
通讯作者：
A. Catapano
中科院分区：
文献类型：
--
作者：
A. Filippi;E. Tragni;A. Bignamini;E. Sessa;G. Merlini;O. Brignoli;G. Mazzaglia;A. Catapano
中风分别是世界范围内第二和第七大死亡和致残原因。缺血性卒中或短暂性脑缺血发作（TIA）患者复发风险高，因此需要强化治疗。高胆固醇血症是中风的一个可改变的危险因素。全科医生对意大利卒中或TIA患者血脂异常检测和治疗的态度尚不清楚;因此，我们旨在利用意大利全科医生学院的数据库来解决这个问题。方法对465 061例患者的监测因素（血脂水平、他汀类药物处方和降脂药处方控制血脂水平）的患病率进行分析。结果共有2555例（49%女性和51%男性）诊断为卒中的患者和2755例（52%女性和48%男性）诊断为TIA的患者纳入研究。超过60%的患者报告了血浆总胆固醇（TC），不到一半的患者报告了低密度脂蛋白胆固醇（LDLc）和高密度脂蛋白胆固醇（HDLc）。分别有70.3%和72.8%的患者血浆总胆固醇和LDLc得到控制。当同时考虑LDLc和TC时，控制患者的百分比降至64%。他汀类药物和贝特类药物处方的患者比例很小（分别为16.9%和3.5%）。大多数患者（60.2%）实现了可接受的血脂控制。然而，相对较多的高血脂患者（646例）仍未接受治疗。结论脑卒中或TIA患者血脂水平的监测及干预策略有待完善。欧洲心脏病学会前康复杂志12：159-163 © 2005欧洲心脏病学会
Background Stroke represents worldwide the second and seventh cause of death and invalidity, respectively. Patients with ischaemic stroke or transitory ischaemic attack (TIA) are at high risk of recurrence, therefore requiring intensive treatment. Hypercholesterolaemia is a modifiable risk factor for stroke. The general practitioners attitude towards detection and treatment of dyslipidaemia among patients with stroke or TIA in Italy is unknown; we therefore aimed to address this issue taking advantage of the database of The Italian College of General Practitioners. Methods Prevalence of the monitored factors (lipid levels, statin prescription, and lipid level control with hypolipidaemic agents prescription) were analysed on a patient population of 465 061. Results A total of 2555 (49% women and 51% men) patients with a diagnosis of stroke and 2755 patients (52% women and 48% men) with a diagnosis of TIA were included in the study. Total plasma cholesterol (TC) was reported in more than 60% of the patients and low-density lipoprotein cholesterol (LDLc) and high-density lipoprotein cholesterol (HDLc) in less than half. Total plasma cholesterol and LDLc were controlled in 70.3 and 72.8% of the patients, respectively. The percentage of controlled patients decreased to 64% when both LDLc and TC were considered. Statins and fibrates were prescribed in a small proportion of patients (16.9 and 3.5%, respectively). An acceptable control of blood lipids was achieved in a majority of those patients (60.2%). However a relatively large number of patients (646) with high plasma lipids remained untreated. Conclusions Monitoring and intervention strategies on plasma lipid levels in patients with a diagnosis of stroke or TIA need to be improved. Eur J Cardiovasc Prev Rehabil 12: 159–163 © 2005 The European Society of Cardiology
影响因子：
120.7
作者：
Sacco, RL;Benson, RT;Berglund, L
通讯作者：
Berglund, L
影响因子：
158.5
作者：
O'Leary, DH;Polak, JF;Wolfson, SK
通讯作者：
Wolfson, SK