Decoding tumor microenvironments through artificial tumor transcriptomes.
Decoding tumor microenvironments through artificial tumor transcriptomes.
复制标题
通过人工肿瘤转录组解码肿瘤微环境。
DOI：
10.1016/j.ccell.2022.07.008
复制
发表时间：
2022-08-08
期刊：
影响因子：
50.3
通讯作者：
Zhang, Jinghui
中科院分区：
文献类型：
--
作者：
Tian, Liqing;Zhang, Jinghui
在这一期的《癌细胞》杂志中，Zaitsev等人提出了一种基于机器学习的方法，该方法是从数百万个混合细胞群的人工转录组中训练出来的，用于重建肿瘤微环境（TME）。这种方法的高准确性，通过广泛的验证证明，使TME在研究和临床环境中的系统调查。
In this issue of Cancer Cell, Zaitsev et al present a machine-learning based approach, trained from millions of artificial transcriptomes with admixed cell populations, for reconstructing tumor microenvironment (TME). The high accuracy of this approach, demonstrated through extensive validation, enables systematic investigation of TME in both research and clinical setting.
登录
查看更多内容
影响因子：
8.8
作者：
Saltz J;Gupta R;Hou L;Kurc T;Singh P;Nguyen V;Samaras D;Shroyer KR;Zhao T;Batiste R;Van Arnam J;Cancer Genome Atlas Research Network;Shmulevich I;Rao AUK;Lazar AJ;Sharma A;Thorsson V
通讯作者：
Thorsson V
影响因子：
30.8
作者：
Lonsdale, John;Thomas, Jeffrey;Salvatore, Mike;Phillips, Rebecca;Lo, Edmund;Shad, Saboor;Hasz, Richard;Walters, Gary;Garcia, Fernando;Young, Nancy;Foster, Barbara;Moser, Mike;Karasik, Ellen;Gillard, Bryan;Ramsey, Kimberley;Sullivan, Susan;Bridge, Jason;Magazine, Harold;Syron, John;Fleming, Johnelle;Siminoff, Laura;Traino, Heather;Mosavel, Maghboeba;Barker, Laura;Jewell, Scott;Rohrer, Dan;Maxim, Dan;Filkins, Dana;Harbach, Philip;Cortadillo, Eddie;Berghuis, Bree;Turner, Lisa;Hudson, Eric;Feenstra, Kristin;Sobin, Leslie;Robb, James;Branton, Phillip;Korzeniewski, Greg;Shive, Charles;Tabor, David;Qi, Liqun;Groch, Kevin;Nampally, Sreenath;Buia, Steve;Zimmerman, Angela;Smith, Anna;Burges, Robin;Robinson, Karna;Valentino, Kim;Bradbury, Deborah;Cosentino, Mark;Diaz-Mayoral, Norma;Kennedy, Mary;Engel, Theresa;Williams, Penelope;Erickson, Kenyon;Ardlie, Kristin;Winckler, Wendy;Getz, Gad;DeLuca, David;MacArthur, Daniel;Kellis, Manolis;Thomson, Alexander;Young, Taylor;Gelfand, Ellen;Donovan, Molly;Meng, Yan;Grant, George;Mash, Deborah;Marcus, Yvonne;Basile, Margaret;Liu, Jun;Zhu, Jun;Tu, Zhidong;Cox, Nancy J.;Nicolae, Dan L.;Gamazon, Eric R.;Im, Hae Kyung;Konkashbaev, Anuar;Pritchard, Jonathan;Stevens, Matthew;Flutre, Timothee;Wen, Xiaoquan;Dermitzakis, Emmanouil T.;Lappalainen, Tuuli;Guigo, Roderic;Monlong, Jean;Sammeth, Michael;Koller, Daphne;Battle, Alexis;Mostafavi, Sara;McCarthy, Mark;Rivas, Manual;Maller, Julian;Rusyn, Ivan;Nobel, Andrew;Wright, Fred;Shabalin, Andrey;Feolo, Mike;Sharopova, Nataliya;Sturcke, Anne;Paschal, Justin;Anderson, James M.;Wilder, Elizabeth L.;Derr, Leslie K.;Green, Eric D.;Struewing, Jeffery P.;Temple, Gary;Volpi, Simona;Boyer, Joy T.;Thomson, Elizabeth J.;Guyer, Mark S.;Cathy Ng;Abdallah, Assya;Colantuoni, Deborah;Insel, Thomas R.;Koester, Susan E.;Little, A. Roger;Bender, Patrick K.;Lehner, Thomas;Yao, Yin;Compton, Carolyn C.;Vaught, Jimmie B.;Sawyer, Sherilyn;Lockhart, Nicole C.;Demchok, Joanne;Moore, Helen F.
通讯作者：
Moore, Helen F.
影响因子：
50.3
作者：
Zaitsev, Aleksandr;Chelushkin, Maksim;Bagaev, Alexander
通讯作者：
Bagaev, Alexander
影响因子：
48
作者：
Newman AM;Liu CL;Green MR;Gentles AJ;Feng W;Xu Y;Hoang CD;Diehn M;Alizadeh AA
通讯作者：
Alizadeh AA
影响因子：
13.6
作者：
Menden, Kevin;Marouf, Mohamed;Bonn, Stefan
通讯作者：
Bonn, Stefan