Cerebrovascular NADPH diaphorase-containing nerve fibers in the rat
Cerebrovascular NADPH diaphorase-containing nerve fibers in the rat
复制标题
大鼠脑血管含 NADPH 心肌黄酶的神经纤维
DOI：
10.1016/0304-3940(93)90030-o
复制
发表时间：
1993
影响因子：
2.5
通讯作者：
Toshihiko Shimizu
中科院分区：
文献类型：
--
作者：
N. Suzuki;Y. Fukuuchi;A. Koto;Y. Naganuma;K. Isozumi;S. Matsuoka;J. Gotoh;Toshihiko Shimizu
Recently, neuronal nicotinamide adenine dinucleotide phosphate (NADPH)-diaphorase has been elucidated to be the nitric oxide synthase (NOS) per se. In order to examine the existence and distribution of cerebrovascular nerve fibers containing these substances, NADPH-diaphorase histochemistry was applied to the cerebral blood vessels and the cranial ganglia known to innervate the cerebral vessels in the rat. Numerous nerve fibers with varicosities forming plexuses were observed in the circle of Willis and its branches. In addition, thick nerve bundles were seen to run along the wall of the internal ethmoidal artery. NADPH-diaphorase reaction was prominent in neurons of the sphenopalatine, otic and internal carotid ganglia. This study demonstrated, for the first time, the NADPH-diaphorase-containing nerve fibers in the cerebral vessels and ganglion cells in the parasympathetic and sensory ganglia known to innervate the cerebral vessels.
DOI：
10.1073/pnas.88.17.7797
发表时间：
1991-09-01
影响因子：
11.1
作者：
DAWSON, TM;BREDT, DS;SNYDER, SH
通讯作者：
SNYDER, SH