Pseudogenes are not pseudo any more

Pseudogenes are not pseudo any more
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假基因不再是假的

DOI:
10.4161/rna.9.1.18277
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发表时间:
2012-01
期刊:
影响因子:
4.1
通讯作者:
Zhao-Rong Lun
Zhao-Rong Lun
中科院分区:
生物学3区
文献类型:
--
作者:
Yan-Zi Wen;Ling-Ling Zheng;Liang-Hu Qu;Francisco J Ayala;Zhao-Rong Lun

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最近在了解原生动物(布氏锥虫)、后生动物(小鼠)和植物中假基因的功能方面取得了重大进展,因此有必要对这个令人着迷的主题的了解进行简要概述。我们讨论了转录后水平的假基因的调控机制,并提出了理解这些假基因(有时被称为“垃圾基因”或“垃圾 DNA”)进化的新想法,旨在激发科学家的兴趣和对该主题的进一步研究。我们希望这一观点能够对正在或寻求研究这些及相关问题的科学家有所帮助。
Recent significant progress toward understanding the function of pseudogenes in protozoa (Trypanosoma brucei), metazoa (mouse) and plants, make it pertinent to provide a brief overview on what has been learned about this fascinating subject. We discuss the regulatory mechanisms of pseudogenes at the post-transcriptional level and advance new ideas toward understanding the evolution of these, sometimes called “garbage genes” or “junk DNA,” seeking to stimulate the interest of scientists and additional research on the subject. We hope this point-of-view can be helpful to scientists working or seeking to work on these and related issues.
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