A portable experimental apparatus for human olfactory fMRI experiments
A portable experimental apparatus for human olfactory fMRI experiments
复制标题
一种用于人体嗅觉功能磁共振实验的便携式实验装置
DOI：
10.1016/j.jneumeth.2013.04.021
复制
发表时间：
2013
影响因子：
3
通讯作者：
M. Bensafi
中科院分区：
文献类型：
--
作者：
C. Sezille;B. Messaoudi;A. Bertrand;P. Joussain;M. Thévenet;M. Bensafi
人类的嗅觉感知可以使用心理物理学工具或更复杂的气味产生装置系统（即嗅觉计）来测量。本论文的目的是提出一种新的廉价，非体积便携式嗅觉仪适用于人类功能磁共振成像实验。该系统调整气味刺激呈现人类鼻腔呼吸，并在同一实验装置中记录行为反应。通过心理物理测量和光电离检测的验证表明，气味强度感知和蒸汽浓度作为气味剂浓度的函数线性增加。通过大脑成像的进一步验证揭示了典型嗅觉区域的神经激活。总之，该系统代表了一种新的低成本，易于使用，易于维护的便携式嗅觉测量工具的大脑成像，开辟了新的可能性，调查神经反应的气味使用事件相关的功能磁共振成像设计。
Human olfactory perception can be measured using psychophysical tools or more complex odor generating devices systems, namely olfactometers. The present paper is aimed at presenting a new inexpensive, non-voluminous portable olfactometer adapted for human fMRI experiments. The system adjusts odorant stimulus presentation to human nasal respiration and records behavioral responses in the same experimental device. Validation by psychophysical measures and photo-ionization detection showed a linear increase in both odor intensity perception and vapor concentration as a function of odorant concentration. Further validation by brain imaging revealed neural activation in typical olfactory areas. In summary, the system represents a new low-cost, easy-use, easy-maintenance portable olfactometry tool for brain imaging, opening up new possibilities for investigating neural response to odors using event-related fMRI designs.
影响因子：
3
作者：
Murphy, C;Morgan, CD;Polich, JM
通讯作者：
Polich, JM