INFECTIOUS AND PRESUMED NONINFECTIOUS ENDOPHTHALMITIS AFTER INTRAVITREAL TRIAMCINOLONE ACETONIDE INJECTION
INFECTIOUS AND PRESUMED NONINFECTIOUS ENDOPHTHALMITIS AFTER INTRAVITREAL TRIAMCINOLONE ACETONIDE INJECTION
复制标题
玻璃体内注射曲安奈德后感染性和推测的非感染性内眼炎
DOI：
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发表时间：
2003
期刊：
影响因子：
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通讯作者：
A. Martidis
中科院分区：
文献类型：
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作者：
M. Nelson;A. Sivalingam;C. Regillo;J. Belmont;A. Martidis
目的报道玻璃体内注射曲安奈德引起的细菌性眼内炎和推定的非感染性眼内炎的潜在区别特征。方法回顾性分析2例经培养证实的细菌性眼内炎和6例经推定为非感染性眼内炎的玻璃体注射曲安奈德患者的临床资料。结果经培养证实的细菌性眼内炎2例患者，在玻璃体内注射曲安奈德2周后，2眼视力下降，出现低视或玻璃体炎，但无疼痛和结膜注射。假定为非感染性眼内炎的6例患者中有7只眼在玻璃体内注射曲安奈德后2天内出现视力模糊、低视和变异性疼痛。所有7只眼均密切随访，视力低下及症状均迅速消退。结论玻璃体内注射曲安奈德后细菌性眼内炎可能以不典型、相对延迟的方式出现，视力下降，无疼痛、红肿。假定在注射后2天内出现非感染性眼内炎，可能伴有不适，可能是曲安奈德材料本身或无菌炎症反应。在这些眼睛中，视力减退和症状无需治疗即可迅速消退。
Purpose To report potentially distinguishing characteristics between bacterial endophthalmitis and presumed noninfectious endophthalmitis associated with intravitreal triamcinolone acetonide injection. Methods Records of two patients with culture-proven bacterial endophthalmitis and six patients with presumed noninfectious endophthalmitis from intravitreal triamcinolone acetonide injections were analyzed retrospectively. Results Two eyes in two patients with culture-proven bacterial endophthalmitis had decreased vision and hypopyon or vitritis, but no pain or conjunctival injection 2 weeks after intravitreal triamcinolone acetonide injection. Seven eyes in six patients with presumed noninfectious endophthalmitis had blurred vision, hypopyon, and variable pain all within 2 days of intravitreal triamcinolone injection. All seven eyes were followed up closely and had rapid resolution of hypopyon and symptoms. Conclusion Bacterial endophthalmitis after intravitreal triamcinolone acetonide injection may present in an atypical, relatively delayed manner with decreased vision but no pain or redness. Presumed noninfectious endophthalmitis presents within 2 days after the injection, may be accompanied by discomfort, and has a hypopyon that may be the triamcinolone material itself or a sterile inflammatory reaction. In these eyes, the hypopyon and symptoms quickly resolve without treatment.
影响因子：
13.7
作者：
CANTRILL, HL;HENRY, K;BALFOUR, HH
通讯作者：
BALFOUR, HH
影响因子：
4.2
作者：
SCHINDLER, RH;CHANDLER, D;MACHEMER, R
通讯作者：
MACHEMER, R