Hippocampal and amygdaloid interactions in the nucleus accumbens
Hippocampal and amygdaloid interactions in the nucleus accumbens
复制标题
海马和杏仁核在伏隔核中的相互作用
DOI：
--
复制
发表时间：
1999
期刊：
影响因子：
--
通讯作者：
C. Pennartz
中科院分区：
文献类型：
--
作者：
H. Groenewegen;A. B. Mulder;ARNO V.J. Beijer;C. I. Wright;F. H. Lopes da Silva;C. Pennartz
The nucleus accumbens, in view of its afferent and efferent fiber connections, appears to hold a key position for “limbic” (e.g., hippocampal and amygdaloid) influences to reach somatomotor and autonomic brain structures, and it has therefore been considered as a limbic-motor interface. The nucleus accumbens can be subdivided into a shell and a core region, which both contain further inhomogeneities. The present account first summarizes the detailed topographical anatomical relationships of inputs from different dorso-ventral parts of the hippocampus and different rostrocaudal parts of the basal amygdaloid complex at the level of the accumbens. Subsequently, the electrophysiological characteristics of hippocampal and amygdaloid inputs in the accumbens are described. Interactions between hippocampal and amygdaloid inputs appear to exist primarily in the medial parts of both the shell and the core of the nucleus accumbens. In the short term, stimulating amygdaloid inputs appear to facilitate hippocampal throughput (heterosynaptic paired pulse facilitation), whereas stimulation of hippocampal inputs depresses amygdaloid throughput in a paired pulse paradigm. Tetanic stimulation of hippocampal inputs to the accumbens leads to a decremental long-term potentiation (LTP) of this fiber pathway (homosynaptic LTP) but, along a similar time range, to a depression of amygdaloid inputs (heterosynaptic long-term depression). The involvement of dopaminergic, GABAergic, and glutamatergic mechanisms in these interactions is discussed. Finally, it is suggested that the interactions between hippocampal and amygdaloid inputs at the level of the nucleus accumbens play a role in different aspects of associative learning.
影响因子：
56.9
作者：
WILSON, MA;MCNAUGHTON, BL
通讯作者：
MCNAUGHTON, BL
大鼠伏隔核神经元的内向整流。
影响因子：
2.5
作者：
Uchimura,N;Cherubini,E;North,RA
通讯作者：
North,RA
解读海马多语言：海马作为路径整合系统。
DOI：
10.1242/jeb.199.1.173
发表时间：
1996
期刊：
The Journal of experimental biology
影响因子：
--
作者：
McNaughton,BL;Barnes,CA;Gerrard,JL;Gothard,K;Jung,MW;Knierim,JJ;Kudrimoti,H;Qin,Y;Skaggs,WE;Suster,M;Weaver,KL
通讯作者：
Weaver,KL