Pigeon crop-sac as a model system for studying the direct and indirect effects of hormones and growth factors on cell growth and differentiation in vivo.

Pigeon crop-sac as a model system for studying the direct and indirect effects of hormones and growth factors on cell growth and differentiation in vivo.
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鸽嗉囊作为研究激素和生长因子对体内细胞生长和分化的直接和间接影响的模型系统。

DOI:
10.1002/jez.1402560413
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发表时间:
1990
期刊:
The Journal of experimental zoology. Supplement : published under auspices of the American Society of Zoologists and the Division of Comparative Physiology and Biochemistry
影响因子:
--
通讯作者:
Nicoll,CS
Nicoll,CS
中科院分区:
--
文献类型:
--
作者:
Nicoll,CS

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鸽子作物囊是一种未被充分认识和利用的模型,可用于研究激素,生长因子和其他药物对体内细胞增殖和分化过程的直接和间接影响。因此,它可以避免许多体外方法的不确定性。此外,作物粘膜细胞是同质的,并且器官在结构上比大多数其他激素反应性靶器官(如乳腺或前列腺)复杂得多。该器官非常适合其他各种研究,例如分析PRL和生长因子的第二信使系统以及生长抑制物质的影响。
The pigeon crop‐sac is an underappreciated and underutilized model that can be used to study the direct and indirect effects of hormones, growth factors, and other agents on cell proliferation and differentiative processes in vivo. It can thus allow the uncertainties that attend many in vitro methods to be avoided. In addition, the crop mucosal cells are homogeneous and the organ is structurally much less complex than most other hormone‐responsive target organs, such as the mammary gland or prostate. The organ is well suited for various other studies such as analysis of second‐messenger systems for PRL and growth factors and the effects of growth‐inhibitory substances.
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