Transhiatal vs extended transthoracic resection in oesophageal carcinoma: patients' utilities and treatment preferences.
Transhiatal vs extended transthoracic resection in oesophageal carcinoma: patients' utilities and treatment preferences.
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DOI：
10.1038/sj.bjc.6600203
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发表时间：
2002-03-18
影响因子：
8.8
通讯作者：
中科院分区：
文献类型：
--
作者：
评估食管癌经食管或经胸食管癌切除术后患者健康状况的效用，并调查患者对这两种手术的治疗偏好。研究组包括48例经食管或经胸食管切除术的患者。在一次访谈中，他们被告知食道切除术后可能出现的八种健康状况。使用视觉模拟量表和标准赌博技术来测量效用。评估了经口或经胸食道切除术的治疗偏好。患者自身目前的健康状况得分最高（视觉模拟量表：0.77；标准赌博：0.97）。健康状态“不可切除的肿瘤”的得分最低（视觉模拟评分：0.13；标准赌博：0.34）。视觉模拟量表法对所有健康状态的估计值均低于标准赌博法（P<0.001）。大多数患者的特征和临床因素与效用无关。95%的经胸腔镜手术患者和52%的经胸腔镜切除术患者更倾向于经胸腔镜治疗。没有发现任何患者特征或临床特征与治疗偏好之间的显著关联。经口或经胸食道切除术后的效用是稳健的，因为它们通常不会因患者或临床特征而变化。总的来说，大多数患者更喜欢经胸手术。英国癌症杂志（2002）86,851-857。DOI: 10.1038/sj/bjc/6600203 www.bjcancer.com©2002英国癌症研究中心
To assess patients' utilities for health state outcomes after transhiatal or transthoracic oesophagectomy for oesophageal cancer and to investigate the patients' treatment preferences for either procedure. The study group consisted of 48 patients who had undergone either transhiatal or transthoracic oesophagectomy. In an interview they were presented with eight possible health states following oesophagectomy. Visual Analogue Scale and standard gamble techniques were used to measure utilities. Treatment preference for either transhiatal or transthoracic oesophagectomy was assessed. Highest scores were found for the patients' own current health state (Visual Analogue Scale: 0.77; standard gamble: 0.97). Lowest scores were elicited for the health state ‘irresectable tumour’ (Visual Analogue Scale: 0.13; standard gamble: 0.34). The Visual Analogue Scale method produced lower estimates (P<0.001) than the standard gamble method for all health states. Most patient characteristics and clinical factors did not correlate with the utilities. Ninety-five per cent of patients who underwent a transthoracic procedure and 52% of patients who underwent a transhiatal resection would prefer the transthoracic treatment. No significant associations between any patient characteristics or clinical characteristics and treatment preference were found. Utilities after transhiatal or transthoracic oesophagectomy were robust because they generally did not vary by patient or clinical characteristics. Overall, most patients preferred the transthoracic procedure. British Journal of Cancer (2002) 86, 851–857. DOI: 10.1038/sj/bjc/6600203 www.bjcancer.com © 2002 Cancer Research UK
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影响因子：
120.7
作者：
Weinstein, MC;Siegel, JE;Russell, LB
通讯作者：
Russell, LB
影响因子：
11.8
作者：
deHaes, JCJM;Stiggelbout, AM
通讯作者：
Stiggelbout, AM
影响因子：
3.6
作者：
BASS, EB;STEINBERG, EP;JOHNS, C
通讯作者：
JOHNS, C
影响因子：
3.6
作者：
STIGGELBOUT, AM;KIEBERT, GM;DEHAES, JCJM
通讯作者：
DEHAES, JCJM
影响因子：
4.2
作者：
Brown, MM;Brown, GC;Shah, G
通讯作者：
Shah, G