Scars of COVID-19: A bibliometric analysis of post-COVID-19 fibrosis.
Scars of COVID-19: A bibliometric analysis of post-COVID-19 fibrosis.
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DOI：
10.3389/fpubh.2022.967829
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发表时间：
2022
影响因子：
5.2
通讯作者：
Xing, Shun-Peng
中科院分区：
文献类型：
--
作者：
Zhong, Han;Zhou, Yang;Mei, Shu-Ya;Tang, Ri;Feng, Jin-Hua;He, Zheng-Yu;Xu, Qiao-Yi;Xing, Shun-Peng
2019冠状病毒病（COVID - 19）已成为全球公共卫生威胁。越来越多的证据表明，COVID - 19引发的急性损伤可通过一些治疗方法得到逆转。此后，COVID - 19后纤维化（PCF）作为“长新冠”的一种后遗症，迅速引发广泛关注。PCF与肺功能恶化和生活质量下降相关。但PCF的发病过程仍存在诸多猜测。因此，我们旨在进行一项文献计量学分析，以探究PCF的整体结构、研究热点及趋势性主题。
我们在Web of Science核心数据库中进行了全面检索，以收集关于PCF的文献。检索语法包括与COVID - 19相关的术语：“COVID 19”“COVID - 19病毒病”“COVID - 19病毒感染”“冠状病毒病 - 19”“2019新型冠状病毒病”“2019新型冠状病毒感染”“严重急性呼吸综合征冠状病毒2感染”“COVID - 19大流行”“冠状病毒”“2019 - nCoV”以及“SARS - CoV - 2”；以及与纤维化相关的术语：“纤维化”“纤维变性”和“肝硬化”。纳入英文文献。共纳入1088篇出版物。随后导出检索结果并收集起来用于文献计量学分析。分别通过R语言中的biblioshiny程序包、VOSviewer软件、CiteSpace软件以及图形聚类工具包（gCLUTO）软件，对国家、机构和个人层面的数据进行分析和可视化处理。
本项文献计量学分析对PCF领域的内在结构和发展情况进行了研究。出现频次最高的关键词是“COVID - 19”（出现频次636次），其周围相关的关键词有“SARS - CoV - 2”（出现频次242次）、“冠状病毒”（出现频次123次）、“纤维化”（出现频次120次）以及“肺炎”（出现频次94次）。对PCF的流行病学、生理病理学、诊断及治疗进行了广泛研究。在此之后，基于对关键词的动态分析，通过突发检测发现，热门主题从“武汉”“炎症”和“细胞因子风暴”急剧转变为“生活质量”和“感染”；通过主题演变，从“急性呼吸综合征”“囊性纤维化”和“纤维化”转变为“感染”“COVID - 19”“生活质量”；从“酶”转变为“新冠后”。同样，共被引参考文献分析表明，被引次数最多的参考文献主题从“肺部病理学”（聚类0）转变为“COVID - 19疫苗接种”（聚类6）。此外，还揭示了贡献者、影响力及合作情况的概况。总体而言，美国在发文量、影响力和合作方面表现最为突出。法国迪塞大学、伦敦帝国理工学院、哈佛大学和华盛顿大学分别在出版物数量、被引次数、H指数和共同作者数量方面位居前列。达纳·阿尔邦是发文量和被引次数最多且共同作者联系强度最强的作者。《囊性纤维化杂志》在多产且有影响力的期刊中排名第一。
本研究所得结果有助于专业人士更好地认识PCF，并为未来实践提供指导。在PCF研究的早期阶段，流行病学、发病机制和治疗方法是研究热点。随着COVID - 19大流行的蔓延以及该领域的进展，近期的关注点已转移到患者的生活质量和新冠后合并症上。尽管如此，与COVID - 19相关的感染和疫苗接种被认为是当前及未来感兴趣的研究趋势。鼓励开展国际合作以及深入的实验室实验，以推动PCF领域的进一步探索。
The coronavirus disease 2019 (COVID-19) becomes a worldwide public health threat. Increasing evidence proves that COVID-19-induced acute injuries could be reversed by a couple of therapies. After that, post-COVID-19 fibrosis (PCF), a sequela of “Long COVID,” earns rapidly emerging concerns. PCF is associated with deteriorative lung function and worse quality of life. But the process of PCF remains speculative. Therefore, we aim to conduct a bibliometric analysis to explore the overall structure, hotspots, and trend topics of PCF. A comprehensive search was performed in the Web of Science core database to collect literature on PCF. Search syntax included COVID-19 relevant terms: “COVID 19,” “COVID-19 Virus Disease,” “COVID-19 Virus Infection,” “Coronavirus Disease-19,” “2019 Novel Coronavirus Disease,” “2019 Novel Coronavirus Infection,” “SARS Coronavirus 2 Infection,” “COVID-19 Pandemic,” “Coronavirus,” “2019-nCoV,” and “SARS-CoV-2”; and fibrosis relevant terms: “Fibrosis,” “Fibroses,” and “Cirrhosis.” Articles in English were included. Totally 1,088 publications were enrolled. Searching results were subsequentially exported and collected for the bibliometric analysis. National, organizational, and individual level data were analyzed and visualized through biblioshiny package in the R, VOSviewer software, the CiteSpace software, and the Graphical Clustering Toolkit (gCLUTO) software, respectively. The intrinsic structure and development in the field of PCF were investigated in the present bibliometric analysis. The topmost keywords were “COVID-19” (occurrences, 636) surrounded by “SARS-CoV-2” (occurrences, 242), “coronavirus” (occurrences, 123), “fibrosis” (occurrences, 120), and “pneumonia” (occurrences, 94). The epidemiology, physiopathology, diagnosis, and therapy of PCF were extensively studied. After this, based on dynamic analysis of keywords, hot topics sharply changed from “Wuhan,” “inflammation,” and “cytokine storm” to “quality of life” and “infection” through burst detection; from “acute respiratory syndrome,” “cystic-fibrosis” and “fibrosis” to “infection,” “COVID-19,” “quality-of-life” through thematic evolution; from “enzyme” to “post COVID.” Similarly, co-cited references analysis showed that topics of references with most citations shift from “pulmonary pathology” (cluster 0) to “COVID-19 vaccination” (cluster 6). Additionally, the overview of contributors, impact, and collaboration was revealed. Summarily, the USA stood out as the most prolific, influential, and collaborative country. The Udice French Research University, Imperial College London, Harvard University, and the University of Washington represented the largest volume of publications, citations, H-index, and co-authorships, respectively. Dana Albon was the most productive and cited author with the strongest co-authorship link strength. Journal of Cystic Fibrosis topped the list of prolific and influential journals. Outcomes gained from this study assisted professionals in better realizing PCF and would guide future practices. Epidemiology, pathogenesis, and therapeutics were study hotspots in the early phase of PCF research. As the spread of the COVID-19 pandemic and progress in this field, recent attention shifted to the quality of life of patients and post-COVID comorbidities. Nevertheless, COVID-19 relevant infection and vaccination were speculated to be research trends with current and future interest. International cooperation as well as in-depth laboratory experiments were encouraged to promote further explorations in the field of PCF.
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影响因子：
3.9
作者：
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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作者：
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通讯作者：
Mendicino F