Senile cataract and ascorbic acid loading

Senile cataract and ascorbic acid loading
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老年性白内障与抗坏血酸负荷

DOI:
10.1111/j.1755-3768.1985.tb06805.x
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发表时间:
1985
影响因子:
3.4
通讯作者:
S. Blika
S. Blika
中科院分区:
医学3区
文献类型:
--
作者:
A. Ringvold;H. Johnsen;S. Blika

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摘要用高效液相色谱法测定了白内障、闭角型青光眼和无晶状体眼患者的血清、房水和晶状体抗坏血酸水平。108例患者被细分为不同的组。对几组患者进行术前血清和房水检测,术后口服抗坏血酸。最后,对手术过程中采集的样本进行了第二次测试。结果表明,白内障眼的抗坏血酸浓度机制需要12h以上的时间才能对负荷刺激产生最大反应。与其他物种相比,这种缓慢的反应令人惊讶,这可能反映了这种疾病中分泌过程本身的影响。
Abstract Serum, aqueous humour, and lens ascorbic acid levels were determined by high‐performance liquid chromatography in cataract‐, closed‐angle glaucoma‐, and aphakic patients. The total number of 108 patients were subdivided into different groups. In several groups the pre‐operative serum and aqueous amounts were tested, whereafter patients in some groups were loaded with ascorbic acid orally. Finally, a second test was performed on samples taken during operation. It turned out that the ascorbic acid concentration mechanism in cataractous eyes needed more than 12 h for maximum reaction on the loading stimulus. The slow reaction is surprising compared to other species, and it may reflect an affection of the secretory process itself in this disease.
DOI: 10.1016/0014-4835(84)90142-8
发表时间: 1984-01-01
影响因子: 3.4
作者:
GIBLIN, FJ;MCCREADY, JP;REDDY, VN
通讯作者: REDDY, VN