Effect of moderate to vigorous physical activity on long-term clinical outcomes and pain severity in fibromyalgia.
Effect of moderate to vigorous physical activity on long-term clinical outcomes and pain severity in fibromyalgia.
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DOI：
10.1002/acr.21980
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发表时间：
2013-08
影响因子：
4.7
通讯作者：
Ang, Dennis C.
中科院分区：
文献类型：
--
作者：
Kaleth, Anthony S.;Saha, Chandan K.;Jensen, Mark P.;Slaven, James E.;Ang, Dennis C.
评估纤维肌痛（FM）患者长期维持中等强度体力活动（MVPA）与临床结果的关系。FM患者（n=170）接受个体化运动处方，并在第12、24和36周使用老年人社区健康活动模型计划（CHAMPS）问卷完成基线和随访身体活动评估。主要结果是纤维肌痛影响问卷-身体损伤（FIQ-PI）评分的变化。次要结果包括整体幸福感（FIQ-Total）、疼痛严重程度评分和抑郁症的改善。将MVPA阈值增加≥10代谢当量小时/周（MET h/周）高于正常活动，27名受试者（15.9%）增加并持续（su - pa）， 68名（40%）增加但随后下降（unsu - pa）， 75名（44.1%）未达到该基准（LO-PA）。与LO-PA组相比，su - pa组和unsu - pa组的FIQ-PI和FIQ-Total均有较大改善（p<0.01）。此外，与LO-PA组相比，su - pa组报告的疼痛严重程度改善更大（p<0.05）。然而，在任何主要或次要结局指标上，su - pa和unsu - pa之间没有显著的组差异。增加MVPA的参与至少12周，可改善FM患者的身体功能和整体健康状况。尽管与非持续性体育活动相比，持续的体育活动与更大的临床益处无关，但这些发现也表明，进行更大量的体育活动与FM疼痛恶化无关。需要进一步的研究来确定持续的MVPA参与与患者预后的后续改善之间的关系。
To evaluate the relationship between long-term maintenance of moderate-vigorous physical activity (MVPA) and clinical outcomes in fibromyalgia (FM). Patients with FM (n=170) received individualized exercise prescriptions and completed baseline and follow-up physical activity assessments using the Community Health Activities Model Program for Seniors (CHAMPS) questionnaire at weeks 12, 24, and 36. The primary outcome was the change in the Fibromyalgia Impact Questionnaire-Physical Impairment (FIQ-PI) score. Secondary outcomes included improvements in overall well-being (FIQ-Total), pain severity ratings, and depression. Using a threshold increase in MVPA of ≥10 metabolic equivalent hours per week (MET h/wk) above usual activities, 27 subjects (15.9%) increased and sustained (SUS-PA), 68 (40%) increased, but then declined (UNSUS-PA), and 75 (44.1%) did not achieve this benchmark (LO-PA). Compared to LO-PA subjects, both SUS-PA and UNSUS-PA subjects reported greater improvement in FIQ-PI (p<0.01) and FIQ-Total (p<0.05). Additionally, the SUS-PA group reported greater improvement in pain severity compared to the LO-PA group (p<0.05). However, there were no significant group differences between SUS-PA and UNSUS-PA for any primary or secondary outcome measure. Increased participation in MVPA for at least 12 weeks improves physical function and overall well-being in patients with FM. Although sustained physical activity was not associated with greater clinical benefit compared to unsustained physical activity, these findings also suggest that performing greater volumes of physical activity is not associated with worsening pain in FM. Future research is needed to determine the relationship between sustained MVPA participation and subsequent improvement in patient outcomes.
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DOI：
10.1097/rhu.0b013e31820e7ea7
发表时间：
2011-03
期刊：
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
影响因子：
--
作者：
Fontaine KR;Conn L;Clauw DJ
通讯作者：
Clauw DJ
影响因子：
4.9
作者：
Häuser W;Klose P;Langhorst J;Moradi B;Steinbach M;Schiltenwolf M;Busch A
通讯作者：
Busch A
影响因子：
2.3
作者：
Jones, Kim D.;Liptan, Ginevra L.
通讯作者：
Liptan, Ginevra L.
影响因子：
4.7
作者：
Mease, Philip J.;Spaeth, Michael;Chappell, Amy S.
通讯作者：
Chappell, Amy S.
影响因子：
2.7
作者：
Pressler, Susan J.;Subramanian, Usha;Sloan, Rebecca
通讯作者：
Sloan, Rebecca