Efficacy of different types of aerobic exercise in fibromyalgia syndrome: a systematic review and meta-analysis of randomised controlled trials.

Efficacy of different types of aerobic exercise in fibromyalgia syndrome: a systematic review and meta-analysis of randomised controlled trials.
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DOI:
10.1186/ar3002
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发表时间:
2010
影响因子:
4.9
通讯作者:
Busch A
Busch A
中科院分区:
医学2区
文献类型:
--
作者:
Häuser W;Klose P;Langhorst J;Moradi B;Steinbach M;Schiltenwolf M;Busch A

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有氧运动(AE)治疗纤维肌痛综合征(FMS)的有效性和最佳类型及量尚未确定。因此,我们评估了FMS中不同类型和数量AE的疗效。对科克伦图书馆、EMBASE、MEDLINE、PsychInfo和SPORTDISCUS(截至2009年4月)以及FMS中AE的原始研究和系统评价的参考文献部分进行了系统综述。纳入了AE与对照(常规治疗、注意安慰剂、活性治疗)相比的随机对照试验(RCT)以及不同类型AE的头对头比较。两位作者使用预定义的数据字段(包括研究质量指标)独立提取文章。共审查了28项比较AE与对照的RCT和7项比较不同类型AE的RCT,共2,494例患者。通过随机效应模型,使用标准化平均差异(95%置信区间)总结效应。AE减轻疼痛(-0.31(-0.46,-0.17); P < 0.001),疲劳(-0.22(-0.38,-0.05); P = 0.009),抑郁情绪(-0.32(-0.53,-0.12); P = 0.002)和健康相关生活质量(HRQOL)的局限性(-0.40(-0.60,-0.20); P < 0.001),改善体能(0.65(0.38,0.95); P < 0.001)。通过陆基和水基AE、轻度至中度强度的运动和每周两次或三次的频率,治疗后疼痛显著减轻。对抑郁情绪、HRQOL和体能的积极影响可在随访时维持。持续锻炼与随访时的积极结果相关。偏倚分析的风险未改变结果的稳健性。很少有研究报告了详细的运动方案,从而限制了不同类型运动的亚组分析。FMS患者的有氧运动计划应包括轻微至中等强度的陆上或水上运动,每周两次或三次,持续至少4周。在参加锻炼计划后,应鼓励患者继续锻炼。
The efficacy and the optimal type and volume of aerobic exercise (AE) in fibromyalgia syndrome (FMS) are not established. We therefore assessed the efficacy of different types and volumes of AE in FMS. The Cochrane Library, EMBASE, MEDLINE, PsychInfo and SPORTDISCUS (through April 2009) and the reference sections of original studies and systematic reviews on AE in FMS were systematically reviewed. Randomised controlled trials (RCTs) of AE compared with controls (treatment as usual, attention placebo, active therapy) and head-to-head comparisons of different types of AE were included. Two authors independently extracted articles using predefined data fields, including study quality indicators. Twenty-eight RCTs comparing AE with controls and seven RCTs comparing different types of AE with a total of 2,494 patients were reviewed. Effects were summarised using standardised mean differences (95% confidence intervals) by random effect models. AE reduced pain (-0.31 (-0.46, -0.17); P < 0.001), fatigue (-0.22 (-0.38, -0.05); P = 0.009), depressed mood (-0.32 (-0.53, -0.12); P = 0.002) and limitations of health-related quality of life (HRQOL) (-0.40 (-0.60, -0.20); P < 0.001), and improved physical fitness (0.65 (0.38, 0.95); P < 0.001), post treatment. Pain was significantly reduced post treatment by land-based and water-based AE, exercises with slight to moderate intensity and frequency of two or three times per week. Positive effects on depressed mood, HRQOL and physical fitness could be maintained at follow-up. Continuing exercise was associated with positive outcomes at follow-up. Risks of bias analyses did not change the robustness of the results. Few studies reported a detailed exercise protocol, thus limiting subgroup analyses of different types of exercise. An aerobic exercise programme for FMS patients should consist of land-based or water-based exercises with slight to moderate intensity two or three times per week for at least 4 weeks. The patient should be motivated to continue exercise after participating in an exercise programme.
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发表时间: 2005-11-01
期刊: RHEUMATOLOGY
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发表时间: 2008-07-01
期刊: PHYSICAL THERAPY
影响因子: 3.2
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期刊: ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
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作者:
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发表时间: 2004-03-01
影响因子: 27.4
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