Comparative study of carpal tunnel compliance in the human, dog, rabbit, and rat.
Comparative study of carpal tunnel compliance in the human, dog, rabbit, and rat.
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DOI：
10.1002/jor.21037
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发表时间：
2010-05
影响因子：
2.8
通讯作者：
Amadio, Peter C.
中科院分区：
文献类型：
--
作者：
Tung, Wen-Lin;Zhao, Chunfeng;Yoshii, Yuichi;Su, Fong-Chin;An, Kin-Nan;Amadio, Peter C.
本研究的目的是测量腕管综合征候选动物模型腕管的顺应性，通过测量将锥形金属棒穿过腕管时的阻力。采用10只狗、10只兔子和10只完整腕管的大鼠的前爪和10具新鲜冷冻的人手腕尸体。力-位移曲线线性部分的斜率（刚度的度量）、法向力和增加面积比（InAR）在四种动物之间有显著差异（p<0.05）。事后分析表明，人类腕管的平均斜率最大，表明依从性最低，而大鼠的平均斜率最小（p<0.05）。犬腕管的顺应性特征与人类最接近。CTS动物模型的开发应考虑腕管的顺应性，因为在更顺应的腕管中增加压力会更困难。
The purpose of this study was to measure the compliance of the carpal tunnel in candidate animal models of carpal tunnel syndrome, by measuring the resistance when passing a tapered metal rod through the carpal tunnel. Forepaws from ten dogs, ten rabbits and ten rats with intact carpal tunnels and ten fresh frozen human wrist cadavers were used. The slopes of the linear part of the force-displacement curve (a measure of stiffness), normal force and increasing area ratio (InAR) were significantly different among the four species (p<0.05). Post hoc analysis indicated that the mean slopes for the human carpal tunnel were the largest indicating the least compliance, while those of the rat were the least (p<0.05). The features of the compliance for the dog carpal tunnel were closest to the human. The development of animal models of CTS should consider the compliance of the carpal tunnel, as it will be more difficult to increase pressure in a more compliant tunnel.
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影响因子：
1.9
作者：
MACKINNON, SE;MCCABE, S;BURKE, GM
通讯作者：
BURKE, GM
影响因子：
1.9
作者：
SILVER, MA;GELBERMAN, RH;RHOADES, CE
通讯作者：
RHOADES, CE
影响因子：
2.8
作者：
Diao, E;Shao, F;Lotz, JC
通讯作者：
Lotz, JC
DOI：
10.2106/00004623-198163030-00009
发表时间：
1981-01-01
影响因子：
5.3
作者：
GELBERMAN, RH;HERGENROEDER, PT;AKESON, WH
通讯作者：
AKESON, WH
影响因子：
120.7
作者：
Atroshi, I;Gummesson, C;Rosén, I
通讯作者：
Rosén, I