Ion source development and radiobiology applications within the LIBRA project

Ion source development and radiobiology applications within the LIBRA project
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LIBRA 项目中的离子源开发和放射生物学应用

DOI:
10.1117/12.888262
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发表时间:
2011
期刊:
--
影响因子:
--
通讯作者:
Borghesi M
Borghesi M
中科院分区:
--
文献类型:
--
作者:
Borghesi M

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鉴于其特性,激光驱动离子束具有在科学、技术和医学领域中创新应用的潜力。其中,一个特别引人注目的应用是用于癌症治疗的粒子疗法,然而,这需要从激光驱动加速器的当前性能进行重大改进。目前在这一领域的研究重点是开发合适的策略,使激光加速离子,以满足这些要求,同时利用激光驱动的过程中的一些独特的功能。LIBRA是一个全英国的联盟,旨在解决这些问题,并开发适用于应用目的的激光驱动离子源,特别关注生物医学应用。我们将报告该财团的活动,旨在优化光束的性能,通过开发和采用先进的瞄准技术,并通过探索新的加速制度,使生产的光束与减少能量扩散。利用皇后大学的TARANIS太瓦激光器,我们发起了一项活动,调查质子辐照生物样品在极端剂量率(> 109 Gy/s)下的影响。
In view of their properties, laser-driven ion beams have the potential to be employed in innovative applications in the scientific, technological and medical areas. Among these, a particularly high-profile application is particle therapy for cancer treatment, which however requires significant improvements from current performances of laser-driven accelerators. The focus of current research in this field is on developing suitable strategies enabling laser-accelerated ions to match these requirements, while exploiting some of the unique features of a laser-driven process. LIBRA is a UK-wide consortium, aiming to address these issues, and develop laser-driven ion sources suitable for applicative purposes, with a particular focus on biomedical applications. We will report on the activities of the consortium aimed to optimizing the properties of the beams, by developing and employing advanced targetry and by exploring novel acceleration regimes enabling production of beams with reduced energy spread. Employing the TARANIS Terawatt laser at Queen's University, we have initiated a campaign investigating the effects of proton irradiation of biological samples at extreme dose rates (> 109Gy/s).
通过微锥目标中的直接激光光压加速,激光加速质子速度超过 65 MeV
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