Candida auris in South Africa, 2012-2016.

Candida auris in South Africa, 2012-2016.
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DOI:
10.3201/eid2411.180368
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发表时间:
2018-11
影响因子:
11.8
通讯作者:
Thomas J
Thomas J
中科院分区:
医学2区
文献类型:
--
作者:
Govender NP;Magobo RE;Mpembe R;Mhlanga M;Matlapeng P;Corcoran C;Govind C;Lowman W;Senekal M;Thomas J

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为了确定南非金黄色念珠菌的流行病学,我们回顾了2012年10月至2016年11月报告确诊和可能侵袭性疾病病例和定植的公共和私营诊断实验室的数据。我们将病例定义为首次从南非任何医疗机构收治的任何年龄的人的任何标本中分离到金黄色葡萄球菌。我们将可能病例定义为诊断实验室使用非确证性生化鉴定方法并培养haemulonii梭菌的病例。我们分析了1692例病例;93%来自私营部门医疗机构,92%来自已知地点的病例来自豪登省。在有可用数据的病例中,29%为侵袭性感染。病例数从18例(2012年10月- 2013年11月)增加到861例(2015年10月- 2016年11月)。我们的研究结果显示,在研究期间,以豪登省的私立医院为中心,金黄色葡萄球菌病例大幅增加。
To determine the epidemiology of Candida auris in South Africa, we reviewed data from public- and private-sector diagnostic laboratories that reported confirmed and probable cases of invasive disease and colonization for October 2012–November 2016. We defined a case as a first isolation of C. auris from any specimen from a person of any age admitted to any healthcare facility in South Africa. We defined probable cases as cases where the diagnostic laboratory had used a nonconfirmatory biochemical identification method and C. haemulonii was cultured. We analyzed 1,692 cases; 93% were from private-sector healthcare facilities, and 92% of cases from known locations were from Gauteng Province. Of cases with available data, 29% were invasive infections. The number of cases increased from 18 (October 2012–November 2013) to 861 (October 2015–November 2016). Our results show a large increase in C. auris cases during the study period, centered on private hospitals in Gauteng Province.
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