UniProt: a worldwide hub of protein knowledge.

UniProt: a worldwide hub of protein knowledge.
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DOI:
10.1093/nar/gky1049
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发表时间:
2019-01-08
影响因子:
14.9
通讯作者:
UniProt Consortium
UniProt Consortium
中科院分区:
生物学2区
文献类型:
--
作者:
UniProt Consortium

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UniProt Knowledgebase是一个序列和注释的集合,涵盖了所有生命分支中超过1.2亿种蛋白质。专家从文献中提取的详细注释已经收集了超过50万个这些蛋白质。这些注释由基于规则的自动化系统提供的注释以及从其他资源导入的注释补充。在本文中,我们描述了我们在过去2年中对资源进行的重大更新。我们已经大大增加了我们提供的参考蛋白质组的数量,特别是我们专注于提高病毒参考蛋白质组的数量。UniProt网站已经增加了新的数据可视化,用于蛋白质的亚细胞定位以及它们的结构和相互作用。UniProt资源可以在CC-BY(4.0)许可证下通过https://www.uniprot.org/网站获得。
The UniProt Knowledgebase is a collection of sequences and annotations for over 120 million proteins across all branches of life. Detailed annotations extracted from the literature by expert curators have been collected for over half a million of these proteins. These annotations are supplemented by annotations provided by rule based automated systems, and those imported from other resources. In this article we describe significant updates that we have made over the last 2 years to the resource. We have greatly expanded the number of Reference Proteomes that we provide and in particular we have focussed on improving the number of viral Reference Proteomes. The UniProt website has been augmented with new data visualizations for the subcellular localization of proteins as well as their structure and interactions. UniProt resources are available under a CC-BY (4.0) license via the web at https://www.uniprot.org/.
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发表时间: 2016-07-21
期刊: Molecular cell
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