Histological and ultrastructural appearance of the hydroxyapatite-bone interface.
Histological and ultrastructural appearance of the hydroxyapatite-bone interface.
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羟基磷灰石-骨界面的组织学和超微结构外观。
DOI：
10.1002/jbm.820240704
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
F.L.J.A. de Wijs
中科院分区：
文献类型：
--
作者：
G. Lange;C. Putter;F.L.J.A. de Wijs
本文描述了骨组织与致密烧结羟基磷灰石（HA）制成的植入物之间在植入床中形成的界面的组织学和超微结构外观。犬受试者的活组织检查包括：（a）用于牙齿替代的加载的粘膜下牙种植体，（B）用于牙槽骨矫正的骨膜下放置的种植体，（c）用于保持拔牙后牙槽嵴形状的骨内放置的牙根种植体。光镜和电镜结果显示种植体表面的骨侧有广泛的骨附着。有一个亲密的，直接的骨接触，没有任何可见的中断。骨为正常板层型，与松质骨连续相连。骨已经生长到植入物最细微的表面不规则处。在距植入物表面小于500 A的距离内观察到钙化骨基质的胶原纤维。骨-植入物界面的薄（20-100 A）电子致密层类似于有机骨基质的界板，也见于骨细胞陷窝的内壁。骨沉积产生生物稳定的骨-植入物界面，而不干扰生理骨转换。这被视为非常有利于植入物到骨的期望的长期固定。
This article describes the histological and ultrastructural appearance of the interface created in the implantation bed, between bone tissue and implants made of dense sintered hydroxyapatite (HA). Biopsies from dog subjects included: (a) loaded permucosal dental implants for tooth substitution, (b) subperiosteally placed implants for alveolar bone correction, (c) endosseously placed dental root implants to retain ridge form following extraction. The light and electron microscopical results show extensive bone apposition on the osseous sides of the implant surfaces. There is an intimate, direct bone contact without any visible interruption. The bone is of normal lamellar type and continuously connected with the trabecular bone. Bone has grown into the finest surface irregularities of the implant. Collagen fibers of the calcified bone matrix are observed within a distance less than 500 A from the implant surface. The thin (20–100 A) electron dense layer at the bone-implant interface resembled the lamina limitans of organic bone matrix, also seen at the inner walls of the osteocytes lacunes. Deposition of bone gives rise to a biologically stable bone-implant interface, without disturbance of the physiological bone turnover. This is seen as very favorable for desired long term fixation of implant to bone.
骨-羟基磷灰石界面的直接电子显微镜研究。
DOI：
10.1002/jbm.820180702
发表时间：
1984
期刊：
Journal of biomedical materials research
影响因子：
--
作者：
Tracy,BM;Doremus,RH
通讯作者：
Doremus,RH