Neural control of energy balance: translating circuits to therapies.
Neural control of energy balance: translating circuits to therapies.
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DOI:
10.1016/j.cell.2015.02.023
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发表时间:
2015-03-26
期刊:
影响因子:
64.5
通讯作者:
Williams KW
中科院分区:
文献类型:
--
作者:
Gautron L;Elmquist JK;Williams KW
Recent insights into the neural circuits controlling energy balance and glucose homeostasis have rekindled the hope for development of novel treatments for obesity and diabetes. However, many therapies contribute relatively modest beneficial gains with accompanying side effects, and the mechanisms of action for other interventions remain undefined. This Review summarizes current knowledge linking the neural circuits regulating energy and glucose balance with current and potential pharmacotherapeutic and surgical interventions for the treatment of obesity and diabetes.
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