Peripheral interactions among single papilla inputs to gustatory nerve fibers.
Peripheral interactions among single papilla inputs to gustatory nerve fibers.
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DOI：
10.1085/jgp.57.1.1
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发表时间：
1971-01
期刊：
影响因子：
--
通讯作者：
Miller IJ Jr
中科院分区：
文献类型：
--
作者：
Miller IJ Jr
记录从大鼠鼓索神经的单纤维，而周边感受器领域进行了映射，使用刺激器开发，以刺激单一的菌状乳头，在大鼠中包含一个孤独的味蕾。结果表明，几个菌状乳头可以提供输入到一个单一的纤维，这些最敏感的乳头提供，平均而言，约一半的纤维刺激整个舌头的反应。对每种浓度的刺激的反应的幅度和浓度-反应曲线的形状在由相同纤维支配的乳头之间不同。如果其中一个乳头供应输入的纤维单独刺激与NaCl溶液，这种刺激的应用程序周围的孤立的乳头舌表面导致增强的纤维反应。如果用NaCl刺激乳头，并将苯甲酸钾溶液施加到周围，则发生反应的抑制。阳离子刺激的兴奋性输入和阴离子刺激的抑制性影响相互作用以确定单个传入纤维的稳态脉冲频率。一个假设的模型，涉及发电机电流的总和沿着的无髓鞘末梢的单个传入神经元的整合输入由同一个单一的纤维支配的几个受体的推测性解释。
Recordings were made from single fibers of the rat chorda tympani nerve while the peripheral receptor fields were mapped using a stimulator developed to stimulate single fungiform papillae which in the rat contain a solitary taste bud. The results indicate that several fungiform papillae may supply input to a single fiber, and the most sensitive papilla of these provided, on the average, about one-half of the response of that fiber to stimulation of the entire tongue. The magnitude of the response to each concentration of stimulus and the shape of the concentration-response curves differ among papillae innervated by the same fiber. If one of the papillae supplying input to the fiber was stimulated individually with NaCl solution, application of this stimulus to the tongue surface surrounding the isolated papilla resulted in enhancement of the fiber response. If the papilla was stimulated with NaCl and potassium benzoate solution was applied to the surround, a depression of the response occurred. The excitatory input of the cationic stimuli and the depressing influence of the anionic stimuli interacted to determine the resultant steady-state impulse frequency of the single afferent fiber. A hypothetical model involving the summation of generator currents along the unmyelinated terminals of the single afferent neuron is presented as a speculative explanation of the integration of inputs from several receptors innervated by the same single fiber.
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影响因子：
--
作者：
FISHMAN, IY
通讯作者：
FISHMAN, IY
影响因子：
--
作者：
Fisii, HS;Malone, PD;Richter, CP
通讯作者：
Richter, CP
DOI：
10.1101/sqb.1965.030.01.007
发表时间：
1965-01-01
期刊：
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY
影响因子：
--
作者：
LOEWENSTEIN, WR
通讯作者：
LOEWENSTEIN, WR
DOI：
10.1111/j.1748-1716.1968.tb04209.x
发表时间：
1968-01-01
期刊：
ACTA PHYSIOLOGICA SCANDINAVICA
影响因子：
--
作者：
HELLEKAN.G
通讯作者：
HELLEKAN.G
影响因子：
2.5
作者：
PFAFFMANN, C
通讯作者：
PFAFFMANN, C