Effect of Uncariae ramulus et Uncus on endothelium in spontaneously hypertensive rats.
Effect of Uncariae ramulus et Uncus on endothelium in spontaneously hypertensive rats.
复制标题
钩藤对自发性高血压大鼠内皮细胞的影响。
DOI：
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发表时间：
1999
期刊：
影响因子：
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通讯作者：
K. Terasawa
中科院分区：
文献类型：
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作者：
H. Goto;Y. Shimada;K. Tanigawa;N. Sekiya;T. Shintani;K. Terasawa
The protective effect of the extract of Uncariae ramulus et Uncus (URE) against endothelium disorder due to hypertension was investigated. We administered low (150 mg/kg/day) and high (450 mg/kg/day) doses of URE orally to spontaneously hypertensive rats for 8 weeks. Endothelium dependent vasodilatation by acetylcholine increased significantly in the high URE group compared with the control group. Endothelium dependent vasocontraction by xanthine oxidase decreased significantly in the high URE group compared with the control group. Serum NO2-/NO3- were tended to increase in the high URE group. It is suggested that URE may have a protective effect for the endothelium against the influence of hypertension.
钙拮抗剂和动脉粥样硬化。
影响因子：
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作者：
Kramsch,DM
通讯作者：
Kramsch,DM