Optical coherence tomography angiography for the detection of macular neovascularization-comparison of en face versus cross-sectional view.
Optical coherence tomography angiography for the detection of macular neovascularization-comparison of en face versus cross-sectional view.
复制标题
DOI:
10.1038/s41433-021-01892-5
复制
发表时间:
2023-02
期刊:
影响因子:
--
通讯作者:
中科院分区:
文献类型:
--
作者:
To evaluate sensitivity and specificity of swept source-optical coherence tomography angiography (SS-OCTA) en face images versus cross-sectional OCTA versus a combination of both for the detection of macular neovascularization (MNV). Prospective cohort study. Consecutive patients with various chorioretinal diseases and subretinal hyperreflective material (SHRM) and/or pigment epithelial detachment (PED) on OCT possibly corresponding to MNV in at least one eye. 102 eyes of 63 patients with fluorescein angiography (FA), OCT and SS-OCTA performed on the same day were included. FA images, the outer retina to choriocapillaris (ORCC) OCTA en face slab, a manually modified en face slab (‘custom slab’), cross-sectional OCTA and a combination of OCTA en face and cross-section were evaluated for presence of MNV. Sensitivity and specificity for MNV detection, as well as the concordance was calculated using FA as the reference. OCTA en face imaging alone yielded a sensitivity of 46.3% (automated)/78.1% (custom) and specificity of 93.4% (automated)/88.5% (custom) for MNV detection. Cross-sectional OCTA (combination with en face) resulted in a sensitivity of 85.4% (82.9%) and specificity of 82.0% (85.3%). Concordance to FA was moderate for automated en face OCTA (κ = 0.43), and substantial for custom en face OCTA (κ = 0.67), cross-sectional OCTA (κ = 0.66) and the combination (κ = 0.68). Segmentation errors result in decreased sensitivity for MNV detection on automatically generated OCTA en face images. Cross-sectional OCTA allows detection of MNV without manual modification of segmentation lines and should be used for evaluation of MNV on OCTA.
登录
查看更多内容
DOI:
10.3928/23258160-20140909-08
发表时间:
2014-09
期刊:
Ophthalmic surgery, lasers & imaging retina
影响因子:
--
作者:
Huang Y;Zhang Q;Thorell MR;An L;Durbin MK;Laron M;Sharma U;Gregori G;Rosenfeld PJ;Wang RK
通讯作者:
Wang RK
影响因子:
4.4
作者:
Lindner, Moritz;Fang, Petra P.;Fleckenstein, Monika
通讯作者:
Fleckenstein, Monika
影响因子:
3.9
作者:
Soomro, T.;Talks, J.
通讯作者:
Talks, J.
影响因子:
--
作者:
Nikolopoulou E;Lorusso M;Micelli Ferrari L;Cicinelli MV;Bandello F;Querques G;Micelli Ferrari T
通讯作者:
Micelli Ferrari T
DOI:
10.1016/j.oret.2017.02.007
发表时间:
2017-07
期刊:
Ophthalmology. Retina
影响因子:
--
作者:
Faridi A;Jia Y;Gao SS;Huang D;Bhavsar KV;Wilson DJ;Sill A;Flaxel CJ;Hwang TS;Lauer AK;Bailey ST
通讯作者:
Bailey ST