Prevalence of four putative periodontopathic bacteria in saliva of a group of Brazilian children with mixed dentition: 1-year longitudinal study.
Prevalence of four putative periodontopathic bacteria in saliva of a group of Brazilian children with mixed dentition: 1-year longitudinal study.
复制标题
一组巴西混合牙列儿童唾液中四种推定牙周病细菌的患病率：一年纵向研究。
DOI：
10.1111/j.1365-263x.2006.00813.x
复制
发表时间：
2007
影响因子：
3.8
通讯作者：
C. Santos
中科院分区：
文献类型：
--
作者：
V. T. Sakai;M. R. Campos;M. Machado;J. Lauris;A. Greene;C. Santos
目的
本研究旨在评估两个不同时间点混合牙列儿童唾液中推定牙周病原体（放线放线杆菌、牙龈卟啉单胞菌、黑普氏菌、齿垢密螺旋体）的患病率，并将这些发现与牙龈健康的临床参数相关联。
设计
采用聚合酶链式反应（PCR）检测方法测定了2003年64名儿童和2004年60名儿童唾液中这些细菌的患病率。通过牙龈指数评估牙龈健康状况。
结果
2003 年和 2004 年，62 名（96.9%）和 50 名（83.3%）儿童牙龈炎症程度较低，而 2 名（3.1%）和 10 名（16.7%）儿童的牙龈炎症评分为中等。大多数儿童（2003 年为 81.3%，2004 年为 73.3%）至少检测到一种细菌。 2003 年和 2003 年，A. actinomycetemcomitans 的患病率为 4.7% 和 1.7%，P. gingivalis 为 6.3% 和 8.3%，P. nigrescens 为 23.4% 和 48.3%（P < 0.05），T. denticola 为 71.9% 和 50%（P < 0.05）。分别为2004年。没有发现牙龈指数与这些细菌的存在以及不同物种的组合之间存在显着关系。
结论
很大比例的儿童在唾液中至少含有一种假定的牙周病原体，但牙周状况良好。
AIM
This study aimed at evaluating the prevalence of putative periodontal pathogens (Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, Prevotella nigrescens, Treponema denticola) in saliva of children with mixed dentition at two different time points, correlating these findings with a clinical parameter of gingival health.
DESIGN
Polymerase chain reaction (PCR) detection was used to determine the prevalence of these bacteria in saliva of 64 children in 2003 and 60 children in 2004. Gingival health was assessed by gingival index.
RESULT
Sixty-two (96.9%) and 50 (83.3%) children presented low gingival inflammation, whereas 2 (3.1%) and 10 (16.7%) had moderate scores in 2003 and 2004, respectively. Majority of the children (81.3% in 2003 and 73.3% in 2004) had detectable levels of at least one of the bacteria. The prevalence found was of 4.7% and 1.7% for A. actinomycetemcomitans, 6.3% and 8.3% for P. gingivalis, 23.4% and 48.3% for P. nigrescens (P < 0.05), and 71.9% and 50% for T. denticola (P < 0.05) in 2003 and 2004, respectively. No significant relationship between gingival index and presence of these bacteria and combination of different species was found.
CONCLUSION
A high percentage of children harboured at least one of the putative periodontal pathogens in saliva, but presented periodontally healthy conditions.
影响因子：
18.6
作者：
Haffajee, A D;Socransky, S S
通讯作者：
Socransky, S S