Baby steps on the road to HIV eradication.
Baby steps on the road to HIV eradication.
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婴儿踏上了根除艾滋病毒的道路。
DOI：
10.1056/nejme1309006
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
S. Hammer
中科院分区：
文献类型：
--
作者：
S. Hammer
强效抗逆转录病毒治疗（ART）对血浆人类免疫缺陷病毒1型（HIV-1） RNA的持久抑制与免疫和临床健康的显着改善以及机会性并发症的发病率和死亡率的降低有关。它还使我们能够恢复正常的预期寿命，有效地消除了艾滋病毒在资源不受限制的环境中接受产前护理的妇女的垂直传播，并可以大大减少水平传播与此同时，将血浆HIV-1 RNA驱动到低于敏感临床分析定量限制的水平的能力揭示了…
The durable suppression of plasma human immunodeficiency virus type 1 (HIV-1) RNA that is conferred by potent antiretroviral therapy (ART) has been associated with dramatic improvements in immunologic and clinical well-being and reductions in morbidity and mortality from opportunistic complications. It has also brought the restoration of normal life expectancies within our grasp, has effectively eliminated the vertical transmission of HIV in resource-unconstrained settings in women who receive antenatal care, and can substantially reduce horizontal transmission.1 Concomitantly, the ability to drive plasma HIV-1 RNA to levels below the limits of quantification of sensitive clinical assays has unveiled the limitations of . . .
影响因子：
32.4
作者：
Shan L;Deng K;Shroff NS;Durand CM;Rabi SA;Yang HC;Zhang H;Margolick JB;Blankson JN;Siliciano RF
通讯作者：
Siliciano RF
DOI：
10.1056/nejmoa1302976
发表时间：
2013-11-07
期刊：
The New England journal of medicine
影响因子：
--
作者：
Persaud D;Gay H;Ziemniak C;Chen YH;Piatak M Jr;Chun TW;Strain M;Richman D;Luzuriaga K
通讯作者：
Luzuriaga K