Wireless Heart Sensor for Capturing Cardiac Orienting Response for Prediction of Neurodevelopmental Delay in Infants.
Wireless Heart Sensor for Capturing Cardiac Orienting Response for Prediction of Neurodevelopmental Delay in Infants.
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DOI：
10.3390/s22239140
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发表时间：
2022-11-25
期刊：
影响因子：
--
通讯作者：
Coleman TP
中科院分区：
文献类型：
--
作者：
Aguilar-Rivera M;Kable JA;Yevtushok L;Kulikovsky Y;Zymak-Zakutnya N;Dubchak I;Akhmedzhanova D;Wertelecki W;Chambers C;Coleman TP
早期识别有神经发育迟缓风险的婴儿是一项重要的公共卫生目标。这种诊断允许对婴儿进行早期干预，最大限度地利用发育中大脑的神经可塑性。使用标准化的生理发育测试，如使用心脏定向反应（CORs）评估神经生理学对环境事件的反应，是早期识别神经发育迟缓的一种有前途和有效的方法。以前的COR是使用大型笨重设备在儿童中收集的，在常规临床访视中进行广泛筛查不可行。我们开发了一种便携式无线心电图（ECG）系统，沿着IOS平板电脑的自定义应用程序，可同时提取具有足够生理和计时精度的COR，以反映对听觉和视觉刺激的良好特征化ECG反应。这里描述的传感器作为确定COR工具在儿童早期筛查中具有成本效益的程度的初始步骤，以确定谁有发展神经认知缺陷的风险，并可能从早期干预中受益。我们证明，我们的方法，基于无线心跳传感器系统和自定义移动的应用程序的刺激显示和数据记录，是足以捕捉COR从婴儿。这里描述的具有移动的技术的COR监测方法是期望的标准化生理评估的示例，其是用于早期识别神经发育延迟的成本和时间有效的可扩展方法。
Early identification of infants at risk of neurodevelopmental delay is an essential public health aim. Such a diagnosis allows early interventions for infants that maximally take advantage of the neural plasticity in the developing brain. Using standardized physiological developmental tests, such as the assessment of neurophysiological response to environmental events using cardiac orienting responses (CORs), is a promising and effective approach for early recognition of neurodevelopmental delay. Previous CORs have been collected on children using large bulky equipment that would not be feasible for widespread screening in routine clinical visits. We developed a portable wireless electrocardiogram (ECG) system along with a custom application for IOS tablets that, in tandem, can extract CORs with sufficient physiologic and timing accuracy to reflect the well-characterized ECG response to both auditory and visual stimuli. The sensor described here serves as an initial step in determining the extent to which COR tools are cost-effective for the early screening of children to determine who is at risk of developing neurocognitive deficits and may benefit from early interventions. We demonstrated that our approach, based on a wireless heartbeat sensor system and a custom mobile application for stimulus display and data recording, is sufficient to capture CORs from infants. The COR monitoring approach described here with mobile technology is an example of a desired standardized physiologic assessment that is a cost-and-time efficient, scalable method for early recognition of neurodevelopmental delay.
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DOI：
10.1111/acer.14525
发表时间：
2021-03
期刊：
Alcoholism, clinical and experimental research
影响因子：
--
作者：
Kable JA;Coles CD;Jones KL;Yevtushok L;Kulikovsky Y;Zymak-Zakutnya N;Dubchak I;Akhmedzhanova D;Wertelecki W;Chambers CD;CIFASD
通讯作者：
CIFASD
DOI：
10.3390/s22052032
发表时间：
2022-03-05
期刊：
Sensors (Basel, Switzerland)
影响因子：
--
作者：
Rogers B;Schaffarczyk M;Clauß M;Mourot L;Gronwald T
通讯作者：
Gronwald T
DOI：
10.1097/01.alc.0000117837.66107.64
发表时间：
2004-03-01
影响因子：
3.2
作者：
Kable, JA;Coles, CD
通讯作者：
Coles, CD
影响因子：
4
作者：
OCONNOR, MJ;COHEN, S;PARMELEE, AH
通讯作者：
PARMELEE, AH
影响因子：
120.7
作者：
May, Philip A.;Chambers, Christina D.;Hoyme, H. Eugene
通讯作者：
Hoyme, H. Eugene