Gut microbiota and migraine.

Gut microbiota and migraine.
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DOI:
10.1016/j.ynpai.2022.100090
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发表时间:
2022-01
期刊:
Neurobiology of pain (Cambridge, Mass.)
影响因子:
--
通讯作者:
Tao F
Tao F
中科院分区:
其他
文献类型:
--
作者:
Crawford J;Liu S;Tao F

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偏头痛是导致成年人残疾的主要原因,也是世界经济的重大负担。对偏头痛根本原因的研究已经跨越了几个世纪,但其根本机制仍未完全了解。近年来,越来越多的证据表明微生物介导的肠-脑串扰可能导致偏头痛的发病机制。这篇综述简要介绍了偏头痛理论的历史,并总结了最近的研究,显示肠道微生物群如何参与偏头痛的病理生理学。还讨论了更好地了解肠道微生物群在偏头痛中的作用的未来研究前景。
Migraine is a leading cause of disability among the adult population and is a significant burden on the economies of the world. Studies into the underlying causes of migraine have spanned centuries but its underlying mechanisms are still not fully understood. In recent years, accumulating evidence implicates that microbiota-mediated gut-brain crosstalk may contribute to the pathogenesis of migraine. This review provides a brief account of the history of migraine theories and summarizes the recent studies showing how gut microbiota is involved in the pathophysiology of migraine. Future research perspectives for better understanding the role of the gut microbiota in migraine are also discussed.
DOI: 10.1177/0333102415620906
发表时间: 2016-10
期刊: Cephalalgia : an international journal of headache
影响因子: --
作者:
Angus-Leppan H;Guiloff RJ
通讯作者: Guiloff RJ