The Bacillus anthracis Cell Envelope: Composition, Physiological Role, and Clinical Relevance.

The Bacillus anthracis Cell Envelope: Composition, Physiological Role, and Clinical Relevance.
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DOI:
10.3390/microorganisms8121864
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发表时间:
2020-11-26
期刊:
影响因子:
4.5
通讯作者:
Fioravanti A
Fioravanti A
中科院分区:
生物学3区
文献类型:
--
作者:
Chateau A;Van der Verren SE;Remaut H;Fioravanti A

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炭疽病是一种由孢子形成细菌病原体炭疽芽孢杆菌引起的高度适应性和致命性疾病。细菌呈现出其细胞包膜的复杂和动态组成,其响应于发育和环境条件以及宿主依赖性信号而变化。由于它们易于进入细胞外位置,B。炭疽菌细胞包膜组分代表了用于鉴定和开发新的治疗和疫苗策略的令人感兴趣的靶标。本文将重点介绍B的组成、生理作用和临床意义。炭疽菌细胞被膜成分。
Anthrax is a highly resilient and deadly disease caused by the spore-forming bacterial pathogen Bacillus anthracis. The bacterium presents a complex and dynamic composition of its cell envelope, which changes in response to developmental and environmental conditions and host-dependent signals. Because of their easy to access extracellular locations, B. anthracis cell envelope components represent interesting targets for the identification and development of novel therapeutic and vaccine strategies. This review will focus on the novel insights regarding the composition, physiological role, and clinical relevance of B. anthracis cell envelope components.
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