A Philosophical Perspective on Evolutionary Systems Biology.

A Philosophical Perspective on Evolutionary Systems Biology.
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DOI:
10.1007/s13752-015-0202-6
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发表时间:
2015-03-01
期刊:
BIOLOGICAL THEORY
影响因子:
--
通讯作者:
Siegal, Mark L.
Siegal, Mark L.
中科院分区:
其他
文献类型:
--
作者:
O'Malley, Maureen A.;Soyer, Orkun S.;Siegal, Mark L.

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进化系统生物学(ESB)是一种新兴的混合方法,它集成了进化和系统生物学的方法,模型和数据。利用2013年ESB跨学科会议上提出的主题,我们详细讨论了进化生物学和系统生物学之间相互作用中出现的一些解释性摩擦。这些紧张关系的出现是因为不同的建模方法,不同的解释目的和策略,以及对进化综合的范围的不同看法。我们将这些讨论置于长期哲学思考的背景下,这些哲学思考涉及解释、建模和理论综合。我们展示了有多少问题的核心ESB的进展可以被理解为一般的哲学问题。解决这些哲学问题的好处也反馈到哲学中,因为ESB为科学哲学和生物哲学的发展提供了科学实践的优秀范例。
Evolutionary systems biology (ESB) is an emerging hybrid approach that integrates methods, models, and data from evolutionary and systems biology. Drawing on themes that arose at a cross-disciplinary meeting on ESB in 2013, we discuss in detail some of the explanatory friction that arises in the interaction between evolutionary and systems biology. These tensions appear because of different modeling approaches, diverse explanatory aims and strategies, and divergent views about the scope of the evolutionary synthesis. We locate these discussions in the context of long-running philosophical deliberations on explanation, modeling, and theoretical synthesis. We show how many of the issues central to ESB’s progress can be understood as general philosophical problems. The benefits of addressing these philosophical issues feed back into philosophy too, because ESB provides excellent examples of scientific practice for the development of philosophy of science and philosophy of biology.
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期刊: BIOLOGICAL THEORY
影响因子: --
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