Sucrose-dependent accumulation of oral streptococci and their adhesion-defective mutants on saliva-coated hydroxyapatite.
Sucrose-dependent accumulation of oral streptococci and their adhesion-defective mutants on saliva-coated hydroxyapatite.
复制标题
口腔链球菌及其粘附缺陷突变体在唾液涂层羟基磷灰石上的蔗糖依赖性积累。
DOI：
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发表时间：
1995
影响因子：
--
通讯作者：
G. Jones
中科院分区：
文献类型：
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作者：
M. Vickerman;G. Jones
口腔链球菌在唾液包覆的羟基磷灰石上的粘附和积聚，研究了出现在初始斑块（多血链球菌FC1和口腔链球菌C5）和更成熟斑块（戈多氏链球菌G9B）中的菌株。菌株FC1和C5洗涤后的细胞与唾液包被的羟基磷灰石的粘附性并不比菌株G9B好，这表明最初的粘附程度并不是这些细菌在牙菌斑中短暂出现的唯一原因。还检查了每个菌株的生长细胞在唾液包被的羟基磷灰石上积累的能力。培养基中添加蔗糖对菌株G9B积累的促进作用大于菌株FC1和C5积累的促进作用。蔗糖还使每个菌株的粘附缺陷突变体的积累达到与亲本菌株相似的水平。这些结果表明，当细菌黏附性降低或膜结合位点受限，黏附受到限制时，蔗糖依赖性的积累可能促进这些口腔链球菌在牙齿表面的定植。
The adhesion and accumulation of oral streptococci on saliva-coated hydroxyapatite was examined in strains representing species that appear in initial plaque (Streptococcus sanguise FC1 and Streptococcus oralis C5) and in more mature plaque (Streptococcus gordonii G9B). Washed cells of strains FC1 and C5 did not attach better to saliva-coated hydroxyapatite than did strain G9B, suggesting that the degree of initial adhesiveness does not alone account for the temporal appearance of these bacteria in dental plaque. Growing cells of each strain were also examined for their ability to accumulate on saliva-coated hydroxyapatite. The addition of sucrose to the medium promoted the accumulation of strain G9B more than it promoted the accumulation of strains FC1 and C5. Sucrose also enhanced the accumulation of adhesion-defective mutants of each strain to levels similar to those of the respective parent strains. These results suggest that sucrose-dependent accumulation may facilitate the colonization of the tooth surface by these species of oral streptococci when adhesion is limited by reduced bacterial adhesiveness or limited pellicle-binding sites.
婴儿口腔链球菌定植。
影响因子：
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作者：
Smith,DJ;Anderson,JM;King,WF;vanHoute,J;Taubman,MA
通讯作者：
Taubman,MA
血链球菌 G9B 粘附素抗原在大肠杆菌中的克隆和表达。
DOI：
10.1099/00221287-135-3-531
发表时间：
1989
期刊：
Journal of general microbiology
影响因子：
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作者：
Rosan,B;Baker,CT;Nelson,GM;Berman,R;Lamont,RJ;Demuth,DR
通讯作者：
Demuth,DR
戈登链球菌中的葡萄糖基转移酶相变以不依赖于蔗糖的方式改变对唾液涂覆的羟基磷灰石表面的粘附。
影响因子：
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作者：
Vickerman,MM;Clewell,DB;Jones,GW
通讯作者：
Jones,GW