Real-Time Delineation of the Central Sulcus with the Spatial Profile of SSEPs Captured with High-Density Ecog Grid
Real-Time Delineation of the Central Sulcus with the Spatial Profile of SSEPs Captured with High-Density Ecog Grid
复制标题
利用高密度 Ecog 网格捕获的 SSEP 空间轮廓实时描绘中央沟
DOI：
10.1109/embc48229.2022.9871900
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Ince, Nuri F.
中科院分区：
文献类型：
--
作者：
Asman, Priscella;Prabhu, Sujit;Tummala, Sudhakar;Ince, Nuri F.
在清醒开颅手术中，皮质标测被广泛用于确定感觉运动区和描绘中央沟(CS)。该方法包括用皮层脑电(ECoG)条电极记录的金标准体感诱发电位(SSEP)。然而，由于条状电极的空间分辨率较差，或者当电极不精确地覆盖所需的皮质区域时，人工峰值解释可能会误解诱发的响应。这可能会导致口才皮层的意外损伤。我们提出了一个基于计算机的软实时可视化系统，它使用记录的带有硬膜下网格的SSEP来辅助皮质标测。用2.4 kHz生物放大器采集了0.6 Hz电刺激正中神经时的神经数据。以双相肌电记录的刺激伪影作为刺激的起点。利用MatLab SIMULINK对ECoG数据进行在线评估，对SSEPs波形进行处理和可视化。可视化系统被编程为在2D网格上将SSEP峰值激活显示为热图，并投影到屏幕上，显示接触表面区域上皮质活动的性质。由于网格占据了很大的皮质表面，热图能够描绘出中央沟。可以在SSEP轨迹上的任何时间点查看地图，而不需要进行峰值解释。为了在皮质标测过程中提供更多的信息，并促进对ECoG网格数据的解释，我们相信这种可视化系统将有助于在手术计划期间快速确定感觉运动区。临床相关性-该实时可视化系统可用于在清醒开颅手术期间在短时间内描绘中央沟。
Cortical mapping is widely employed to define the sensorimotor area and delineate the central sulcus (CS) during awake craniotomies. The approach involves the gold standard somatosensory evoked potentials (SSEPs) recorded with electrocorticogram (ECoG) strip electrodes. However, the evoked response can be misconstrued from the manual peak interpretation due to the poor spatial resolution of the strip electrode or when the electrode does not precisely cover the desired cortical area. This can lead to unintentional damage to the eloquent cortex. We present a soft real-time computer based visualization system that uses recorded SSEPs with a subdural grid to aid in cortical mapping. The neural data during electrical stimulation of the median nerve at 0.6Hz are picked up with a bio-amplifier at 2.4kHz. The stimulation artifact recorded from the bipolar electromyogram (EMG) is used as the stimulation onset. The ECoG data are assessed online with MATLAB Simulink to process and visualize the SSEPs waveform. The visualization system is programmed to display the SSEPs peak activation as a heat map on a 2D grid and projected onto a screen, showcasing the nature of the cortical activities over the contact surface area. Since the grid occupies a large cortical surface, the heatmap is able to delineate the central sulcus. The map can be viewed at any time point along the SSEP trace without the need for peak interpretation. With the goal to provide additional information during cortical mapping and facilitate interpretation of ECoG grid data, we believe that this visualization system will aid in rapid definition of the sensorimotor area during surgical planning. Clinical Relevance- This real-time visualization system can be used to delineate the central sulcus in a short time during awake craniotomies.
影响因子：
5.7
作者：
Miller, Kai J.;denNijs, Marcel;Ojemann, Jeffrey G.
通讯作者：
Ojemann, Jeffrey G.
直接从人类大脑皮层记录的体感诱发高频振荡
影响因子：
4.7
作者：
Y. Maegaki;I. Najm;K. Terada;H. Morris;W. Bingaman;N. Kohaya;A. Takenobu;Yoko Kadonaga;H. Lüders
通讯作者：
H. Lüders