The Omics Dashboard for Interactive Exploration of Metabolomics and Multi-Omics Data.

The Omics Dashboard for Interactive Exploration of Metabolomics and Multi-Omics Data.
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用于代谢组学和多组学数据交互探索的OMICS仪表板。

DOI:
10.3390/metabo14010065
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发表时间:
2024-01-19
期刊:
影响因子:
4.1
通讯作者:
--
中科院分区:
生物学3区
文献类型:
--
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组学仪表板是一个用于交互式探索和分析代谢组学、转录组学、蛋白质组学和多组学数据集的软件工具。作为细胞系统的层次结构,仪表板在其最高级别包含全方位细胞系统的图形面板,包括生物合成,能量代谢和对刺激的反应。因此,仪表板顶层在单个屏幕中跨广泛的关键系统调查单元的状态。每个仪表板面板包含一系列X-Y图,描绘与该面板的不同子系统相关的聚合组学数据值,例如,生物合成组内的子系统包括氨基酸生物合成、碳水化合物生物合成和辅因子生物合成。用户可以交互式地向下钻取,以关注感兴趣的较低级别的子系统。在本文中,我们首次介绍了组学仪表板的代谢组学分析功能,沿着重要的新扩展,以更好地适应代谢组学数据集,实现多组学数据集的分析和可视化,并提供新的数据过滤选项。
The Omics Dashboard is a software tool for interactive exploration and analysis of metabolomics, transcriptomics, proteomics, and multi-omics datasets. Organized as a hierarchy of cellular systems, the Dashboard at its highest level contains graphical panels for the full range of cellular systems, including biosynthesis, energy metabolism, and response to stimulus. Thus, the Dashboard top level surveys the state of the cell across a broad range of key systems in a single screen. Each Dashboard panel contains a series of X–Y plots depicting the aggregated omics data values relevant to different subsystems of that panel, e.g., subsystems within the biosynthesis panel include amino acid biosynthesis, carbohydrate biosynthesis and cofactor biosynthesis. Users can interactively drill down to focus in on successively lower-level subsystems of interest. In this article, we present for the first time the metabolomics analysis capabilities of the Omics Dashboard, along with significant new extensions to better accommodate metabolomics datasets, enable analysis and visualization of multi-omics datasets, and provide new data-filtering options.
DOI: 10.3390/metabo9050088
发表时间: 2019-05-01
期刊: METABOLITES
影响因子: 4.1
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