Functional and physical outcomes following use of a flexible CO2 laser fiber and bipolar electrocautery in close proximity to the rat sciatic nerve with correlation to an in vitro thermal profile model.
Functional and physical outcomes following use of a flexible CO2 laser fiber and bipolar electrocautery in close proximity to the rat sciatic nerve with correlation to an in vitro thermal profile model.
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DOI：
10.1155/2015/280254
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发表时间：
2015
影响因子：
--
通讯作者：
Richter CP
中科院分区：
文献类型：
--
作者：
Robinson AM;Fishman AJ;Bendok BR;Richter CP
本研究比较了在操作Codman MALIS双极电外科系统CMC-III或CO2激光耦合激光时对神经造成的功能和物理附带损伤，并与器械在热致变色墨水琼脂糖中产生的加热曲线的体外模型相关。通过电诱发神经动作电位测量在各种功率设置和神经接近度下操作MALIS或CO2激光后大鼠坐骨神经的功能损伤，并使用神经的组织学来评估物理损伤。使用溶解在琼脂糖中的热致变色墨水来模拟电外科系统的并行加热区和激光消融锥的空间和时间轮廓。我们发现，这种激光器可以在神经正上方以2 W的功率运行，且损伤最小，而5 W和10 W的功率设置会导致急性功能和身体神经损伤，这与热变色墨水模型中的最大加热锥相关。高达40（11 W）的MALIS设置不会导致主要的功能或物理神经损伤，直到神经位于镊子尖端之间，与尖端之间离散定位的最热区相关。
This study compared functional and physical collateral damage to a nerve when operating a Codman MALIS Bipolar Electrosurgical System CMC-III or a CO2 laser coupled to a laser, with correlation to an in vitro model of heating profiles created by the devices in thermochromic ink agarose. Functional damage of the rat sciatic nerve after operating the MALIS or CO2 laser at various power settings and proximities to the nerve was measured by electrically evoked nerve action potentials, and histology of the nerve was used to assess physical damage. Thermochromic ink dissolved in agarose was used to model the spatial and temporal profile of the collateral heating zone of the electrosurgical system and the laser ablation cone. We found that this laser can be operated at 2 W directly above the nerve with minimal damage, while power settings of 5 W and 10 W resulted in acute functional and physical nerve damage, correlating with the maximal heating cone in the thermochromic ink model. MALIS settings up to 40 (11 W) did not result in major functional or physical nerve damage until the nerve was between the forceps tips, correlating with the hottest zone, localized discretely between the tips.
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DOI：
10.1016/s1079-2104(05)80300-2
发表时间：
1995-06-01
影响因子：
--
作者：
WILDERSMITH, P;ARRASTIA, AMA;BERNS, M
通讯作者：
BERNS, M
影响因子：
2
作者：
Consiglieri, Giac D.;Killory, Brendan D.;Spetzler, Robert F.
通讯作者：
Spetzler, Robert F.
影响因子：
2
作者：
Jayarao, Mayur;Devaiah, Anand K.;Chin, Lawrence S.
通讯作者：
Chin, Lawrence S.
影响因子：
2
作者：
Malone, Hani R.;Syed, Omar N.;McKhann, Guy M., II
通讯作者：
McKhann, Guy M., II
影响因子：
2.4
作者：
WALSH, JT;FLOTTE, TJ;DEUTSCH, TF
通讯作者：
DEUTSCH, TF