The influence of demographic factors on phase-modulated spectroscopy in adults.
The influence of demographic factors on phase-modulated spectroscopy in adults.
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人口因素对成人相位调制光谱的影响。
DOI：
10.1098/rstb.1997.0058
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发表时间：
1997
期刊：
影响因子：
--
通讯作者：
Levy,WJ
中科院分区：
文献类型：
--
作者：
Levy,WJ
如果需要测量光程长度，则相位调制光谱与近红外光谱的非相干光技术相比增加的复杂性是合理的。为了评估成人头部光传输的变化，96名不同年龄、性别和皮肤色素沉着的受试者使用实验性三波长分时相位调制光谱装置进行了研究。在每个波长下测量光程长度，并计算饱和度和无血红蛋白光程长度。光路长度随光探头间距呈线性变化，但性别、年龄或皮肤色素沉着与光路长度的差异无关。血红蛋白饱和度平均为68%，并随年龄的变化而变化。无血红蛋白路径长度因性别而异，女性比男性长8%。由于36%的受试者的光学衰减，无法在5厘米处进行测量。这些受试者通常更年轻，但他们没有通过性别或色素沉着差异来区分。受试者中，可以获得测量在5厘米有较长的血红蛋白自由路径长度比受试者中，光学衰减阻止这些测量。这些数据证实了成年人光传输的显着差异的发生，并支持使用相位调制光谱技术测量路径长度。
The increased complexity of phase–modulated spectroscopy compared with incoherent light techniques of near–infrared spectroscopy is justified if measurement of path length is necessary. In order to assess the variability of optical transmission in the head of adults, 96 subjects of varying age, gender and skin pigmentation were studied using an experimental three–wavelength time–shared phase–modulated spectroscopy device. The optical path length was measured at each wavelength, and saturation and haemoglobin–free path length were calculated. The path length varied linearly with the separation of the optical probes, but gender, age or skin pigmentation were not associated with differences in path length. Haemoglobin saturation averaged 68 per cent and varied with age in a non–uniform fashion. Haemoglobin–free path length varied between genders, being 8 per cent longer in women than in men. Measurements could not be performed at 5 cm due to optical attenuation in 36 per cent of subjects These subjects were more often young, but they were not otherwise distinguished by gender or pigmentation differences. Subjects in whom measurements could be obtained at 5 cm had longer haemoglobin–free path lengths than did subjects in whom optical attenuation prevented these measurements. These data confirm the occurrence of significant differences in optical transmission in adults and support the use of phase–modulated spectroscopy techniques that measure path length.
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DOI：
--
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Journal of the National Cancer Institute
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DOI：
10.1111/j.1699-0463.1958.tb04671.x
发表时间：
2009
期刊：
Acta pathologica et microbiologica Scandinavica
影响因子：
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作者：
K. Arnesen
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DOI：
10.1093/jnci/26.1.189
发表时间：
1961
期刊：
Journal of the National Cancer Institute
影响因子：
--
作者：
T. Dunn;J. Moloney;A. W. Green;B. Arnold
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