Influence of intensified adherence counselling on viral load suppression of people receiving antiretroviral therapy at a health centre IV in southwestern Uganda: a qualitative study.
Influence of intensified adherence counselling on viral load suppression of people receiving antiretroviral therapy at a health centre IV in southwestern Uganda: a qualitative study.
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DOI：
10.1186/s12981-021-00372-w
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发表时间：
2021-07-28
影响因子：
2.2
通讯作者：
Novatus N
中科院分区：
文献类型：
--
作者：
Pius A;Josephine NN;Erick S;Winifred A;Rita M;Silverjoseph O;Lucy E;Novatus N
乌干达成人和儿童中人类免疫缺陷病毒（HIV）的流行率分别为6.2%和0.5%。乌干达所有感染艾滋病毒的成人和儿童的病毒载量抑制率分别为59.6%和39.3%。高病毒载量会影响个人的生活质量，也会增加孕妇和配偶将病毒传染给未出生婴儿的风险。联合国艾滋病规划署的90-90-90运动建议90%的人了解自己的状况，90%的人得到治疗，90%的人得到病毒抑制。不坚持抗逆转录病毒治疗（ART）是高病毒载量的原因之一。世界卫生组织建议向所有病毒载量高的个体提供强化依从性咨询。接受IAC的人的看法、态度和做法对于了解如何最好地实施IAC非常重要。在Kyabugimbi第四保健中心[HC IV（由一名医生领导的小型医院）]有目的地选择了30名接受抗逆转录病毒治疗和IAC治疗的儿童的个人/监护人，对他们进行了定性研究。从焦点小组讨论中收集的数据以当地语言（Runyankole）的录音形式进行转录，然后翻译成英语。使用主题内容分析手工分析翻译文本。确定的主要主题包括：坚持抗逆转录病毒治疗；IAC后对ART态度的改变、IAC的期望和结果、IAC与耻辱感，以及通过IAC改善艾滋病毒感染者的社会支持。参加联合行动将提供信息，并导致他们改变对艾滋病毒的看法，更好地了解坚持抗逆转录病毒治疗的原因。IAC影响了态度和行为的改变，从而寻求社会支持并减轻耻辱感，从而更好地坚持抗逆转录病毒治疗。然而，在信息的结构设置和信息的分解和包装方面，都需要改进它的传递方式。
The prevalence of Human Immunodeficiency Virus (HIV) among adults and children in Uganda is 6.2% and 0.5% respectively. The prevalence of viral load suppression in Uganda among all adults and children living with HIV is 59.6% and 39.3% respectively. High viral load compromises on the quality of life of an individual, and as well increases on the risk of transmission of the virus to the unborn for pregnant mothers and to the spouse. The UNAID 90-90-90 campaign recommends that 90% know their status, 90% get treatment and 90% have viral suppression. Non-adherence to Antiretroviral Therapy (ART) is one of the causes of the high viral load. The world health organization recommends Intensified Adherence Counselling (IAC) be given to all individuals with a high viral load. The perceptions, attitudes and practices of people receiving IAC is important in understanding how best IAC should be implemented. A qualitative study was done among 30 purposively selected individuals/guardians of children receiving ART and IAC at Kyabugimbi Health Center Four [HC IV (mini-hospital headed by a medical doctor)]. Data collected from Focus Group Discussion as audio-recordings in local language (Runyankole) was transcribed and later translated into English. Translated transcripts were analyzed manually using thematic content analysis. The major themes identified include: adherence to ART; change of attitude towards ART after IAC, IAC expectation and outcomes, IAC and stigma, and improving social support through IAC for PLWHIV. Participating in IAC to be informative and led to change in their perceptions of HIV and better understanding the reasons for adherence to ART. IAC influenced the change in attitude and behavior thus seeking social support and mitigate stigma, which lead to a better ART adherence. However, there is need to improve on the way it is delivered both in structural setting and break down and packaging of information.
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影响因子：
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作者：
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