Sensory adaptation to electrical stimulation of the somatosensory nerves.
Sensory adaptation to electrical stimulation of the somatosensory nerves.
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DOI：
10.1088/1741-2552/aab790
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发表时间：
2018-08
影响因子：
4
通讯作者：
Tyler DJ
中科院分区：
文献类型：
--
作者：
Graczyk EL;Delhaye BP;Schiefer MA;Bensmaia SJ;Tyler DJ
感觉系统使它们的敏感度适应环境刺激水平，以提高它们对刺激变化的响应性。触觉也受到适应的影响，如由皮肤的长时间振动刺激产生的脱敏所证明的。电刺激残余神经可产生触觉，为仿生肢体提供反馈。在这项研究中，我们调查这种人工触摸是否也受到适应，尽管事实上，机械转导的网站被绕过。我们的特点的时间过程和幅度的感觉适应所造成的延长电刺激的残余体感神经植入袖带电极的三名患者。我们发现，电诱导的适应的时间过程和幅度是非常相似的机械诱导的同行。我们的结论是，在自然的触摸，mechanotransduction的过程是不需要的适应和人工触摸自然经历适应引起的调整的动态范围的感觉。
Sensory systems adapt their sensitivity to ambient stimulation levels to improve their responsiveness to changes in stimulation. The sense of touch is also subject to adaptation, as evidenced by the desensitization produced by prolonged vibratory stimulation of the skin. Electrical stimulation of residual nerves elicits tactile sensations that can convey feedback for bionic limbs. In this study, we investigate whether this artificial touch is also subject to adaptation, despite the fact that the sites of mechanotransduction are bypassed. We characterize the time course and magnitude of the sensory adaptation caused by extended electrical stimulation of the residual somatosensory nerves in three patients implanted with cuff electrodes. We find that the time course and magnitude of electrically induced adaptation are very similar to their mechanically induced counterparts. We conclude that, in natural touch, the process of mechanotransduction is not required for adaptation and artificial touch naturally experiences adaptation-induced adjustments of the dynamic range of sensations.
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影响因子：
17.1
作者：
Graczyk EL;Schiefer MA;Saal HP;Delhaye BP;Bensmaia SJ;Tyler DJ
通讯作者：
Tyler DJ
DOI：
10.1085/jgp.2.5.499
发表时间：
1920-05-20
期刊：
The Journal of general physiology
影响因子：
--
作者：
Hecht S
通讯作者：
Hecht S
影响因子：
2.5
作者：
Bensmaïa, SJ;Leung, YY;Johnson, KO
通讯作者：
Johnson, KO
影响因子：
--
作者：
GESCHEID.GA;WRIGHT, JH
通讯作者：
WRIGHT, JH
影响因子：
4.6
作者：
SZETO, AYJ;SAUNDERS, FA
通讯作者：
SAUNDERS, FA