Invited review: engineering approaches to cytoskeletal mechanics.
Invited review: engineering approaches to cytoskeletal mechanics.
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特邀评论：细胞骨架力学的工程方法。
DOI：
10.1152/jappl.2000.89.5.2085
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发表时间：
2000
期刊：
影响因子：
--
通讯作者：
Wang,N
中科院分区：
文献类型：
--
作者：
Stamenović,D;Wang,N
An outstanding problem in cell biology is how cells sense mechanical forces and how those forces affect cellular functions. Various biophysical and biochemical mechanisms have been invoked to answer this question. A growing body of evidence indicates that the deformable cytoskeleton (CSK), an intracellular network of interconnected filamentous biopolymers, provides a physical basis for transducing mechanical signals into biochemical signals. Therefore, to understand how mechanical forces regulate cellular functions, it is important to know how cells respond to changes in the CSK force balance and to identify the underlying mechanisms that control transmission of mechanical forces throughout the CSK and bring it to equilibrium. Recent developments of new experimental techniques for measuring cell mechanical properties and novel theoretical models of cellular mechanics make it now possible to identify and quantitate the contributions of various CSK structures to the overall balance of mechanical forces in the cell. This review focuses on engineering approaches that have been used in the past two decades in studies of the mechanics of the CSK.
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DOI：
10.1152/ajpcell.2000.279.1.c188
发表时间：
2000-07
期刊：
American journal of physiology. Cell physiology
影响因子：
--
作者：
Ning Wang;D. Stamenović
通讯作者：
Ning Wang;D. Stamenović
DOI：
10.1073/pnas.94.3.849
发表时间：
1997-02-04
影响因子：
11.1
作者：
Maniotis, AJ;Chen, CS;Ingber, DE
通讯作者：
Ingber, DE
DOI：
10.1016/s0034-5687(99)00092-4
发表时间：
2000
期刊：
Respiration physiology
影响因子：
--
作者：
Hubert Wirtz;Leland G. Dobbs
通讯作者：
Hubert Wirtz;Leland G. Dobbs
影响因子：
3.4
作者：
Dembo, M;Wang, YL
通讯作者：
Wang, YL
DOI：
10.1115/1.2895465
发表时间：
1993-02-01
影响因子：
1.7
作者：
FUNG, YC;LIU, SQ
通讯作者：
LIU, SQ