High nasal resistance may be a result rather than a cause of obstructive sleep apnea
High nasal resistance may be a result rather than a cause of obstructive sleep apnea
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高鼻阻力可能是阻塞性睡眠呼吸暂停的结果而不是原因
DOI：
10.1007/s00405-014-3061-z
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发表时间：
2014-05
影响因子：
2.6
通讯作者：
Zhang, Xiaowen
中科院分区：
文献类型：
--
作者：
Song, Lijuan;Li, Yanmei;Zhong, Nanshan;Zhang, Xiaowen
阻塞性睡眠呼吸暂停（OSA）患者表现为高鼻阻力（NR）。本研究验证了OSA患者鼻塞可能由咽部狭窄引起的假设。本研究的目的是探讨悬雍垂腭咽成形术（UPPP）对OSA患者NR的影响。对33例OSA患者进行鼻压测量，并记录其在upppp前后清醒坐位时的Mallampati评分。33名健康志愿者作为对照组。OSA患者NR（0.37±0.22 Pa/cm3/s）显著高于正常对照组（0.19±0.04 Pa/cm3/s） （p< 0.01）。术后NR由0.37±0.22降至0.20±0.05 Pa/cm3/s (p< 0.01)， Mallampati评分由3.00±0.56降至1.52±0.57 （p< 0.01）。但UPPP后NR值仍高于对照组，但两组间差异无统计学意义（p= 0.34）。本研究表明，高NR可能不完全是鼻腔解剖性梗阻所致，而可能是OSA患者咽部狭窄所致。高NR可能是OSA的结果而不是原因。
Patients with obstructive sleep apnea (OSA) show high nasal resistance (NR). The present study tested the hypothesis that nasal obstruction in OSA patients could be caused by pharyngeal narrow. The aim of this study was to investigate the effect of uvulopalatopharyngoplasty (UPPP) on NR in patients with OSA. Rhinomanometry was performed and the Mallampati score was recorded during wakefulness in a sitting position before and after UPPP for 33 patients with OSA. Thirty-three healthy volunteers were used as a control group. The NR in patients with OSA (0.37 ± 0.22 Pa/cm3/s) was significantly higher than that of the normal controls (0.19 ± 0.04 Pa/cm3/s) (p< 0.01). The NR decreased from 0.37 ± 0.22 to 0.20 ± 0.05 Pa/cm3/s (p< 0.01) after UPPP with the Mallampati score decreased from 3.00 ± 0.56 to 1.52 ± 0.57 (p< 0.01). However, NR values after UPPP were still higher than those of the control group, but there was no significant difference between those two groups (p= 0.34). The present study showed that the high NR may not be completely attributable to nasal anatomic obstruction, but may result from pharyngeal narrow in OSA. High NR may be a result of OSA rather than a cause.
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DOI：
10.1097/00005537-200307000-00012
发表时间：
2003-07
期刊：
The Laryngoscope
影响因子：
--
作者：
P. Virkkula;K. Hurmerinta;M. Löytönen;T. Salmi;H. Malmberg;P. Maasilta
通讯作者：
P. Virkkula;K. Hurmerinta;M. Löytönen;T. Salmi;H. Malmberg;P. Maasilta
DOI：
10.1007/s00405-010-1469-7
发表时间：
2011-09
期刊：
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
影响因子：
--
作者：
Georgalas C
通讯作者：
Georgalas C
DOI：
10.1016/j.otohns.2003.09.015
发表时间：
2004-01
期刊：
Otolaryngology–Head and Neck Surgery
影响因子：
--
作者：
F. R. Miller;D. Watson;M. Boseley
通讯作者：
F. R. Miller;D. Watson;M. Boseley
影响因子：
3.7
作者：
Canova, CR;Downs, SH;Leuppi, JD
通讯作者：
Leuppi, JD
影响因子：
1.9
作者：
Dattilo, DJ;Drooger, SA
通讯作者：
Drooger, SA