Evaluation of a treatment approach combining nicotine gum with self-guided behavioral treatments for smoking relapse prevention.

Evaluation of a treatment approach combining nicotine gum with self-guided behavioral treatments for smoking relapse prevention.
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评估将尼古丁口香糖与自我指导行为治疗相结合以预防吸烟复吸的治疗方法。

DOI:
10.1037//0022-006x.58.1.85
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发表时间:
1990
影响因子:
5.9
通讯作者:
Varady,A
Varady,A
中科院分区:
心理学1区
文献类型:
--
作者:
Killen,JD;Fortmann,SP;Newman,B;Varady,A

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1,218名能够戒烟48小时的吸烟者被随机分配到12个单元格中的一个,采用4×3完全交叉析因实验。药理学因素包括四个水平:尼古丁波拉西来司(口香糖)随机或固定方案给药,安慰剂口香糖,和不使用口香糖。自我引导的行为治疗因素包括三个水平:自我选择的复发预防模块、随机给药模块和无模块。那些接受尼古丁口香糖的人在2个月和6个月的随访中更有可能戒烟。固定疗法对口香糖的影响最大。对复发预防模块因子无影响。男性和女性表现出不同的治疗反应。接受尼古丁口香糖的男性在每次随访(2、6和12个月)时更有可能戒烟。在女性中,没有一种治疗明显更好。我们的结论是,有必要对不同的口香糖咀嚼方案进行研究,并需要进一步检查替代疗法可能造成的性别差异。
1,218 smokers able to quit smoking for 48 hr were randomly assigned to one of 12 cells in a 4× 3 fully crossed factorial experiment. A pharmacologic factor contained four levels: nicotine polacrilex (gum) delivered ad lib or on a fixed regimen, placebo gum, and no gum. A self-guided behavioral treatment factor contained three levels: self-selected relapse prevention modules, randomly administered modules, and no modules. Those receiving nicotine gum were more likely to be abstinent at the 2-and 6-month follow-ups. The fixed regimen accounted for most of the effect for gum. There was no effect for the relapse prevention module factor. Men and women showed a differential treatment response. Men who received nicotine gum were more likely to be abstinent at each follow-up (2, 6, and 12 months). No treatment was significantly better among women. We conclude that research on different gum chewing regimens is warranted and that further examination of possible gender differences in response to replacement therapy is needed.(PsycINFO Database Record (c) 2016 APA, all rights reserved)
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